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Catalog Number:
12847
CAS Number:
401620-74-4
Fmoc-2-cyano-D-phenylalanine
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Phe(2-CN)-OH, Fmoc-o-Cyano-D-Phe-OH, (R-Fmoc-2-amino-(2-cyanophenyl)propanoic acid
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$168.35 /1G
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Product Information

Fmoc-2-cyano-D-phenylalanine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound, characterized by its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, is particularly valuable in solid-phase peptide synthesis (SPPS), allowing for the efficient assembly of complex peptides. Its cyano group enhances the compound's reactivity, making it an excellent choice for researchers focused on developing novel therapeutics or studying protein interactions.

In addition to its applications in peptide synthesis, Fmoc-2-cyano-D-phenylalanine can be utilized in the design of bioactive compounds, contributing to advancements in medicinal chemistry. Its ability to facilitate the introduction of diverse functionalities into peptide chains opens avenues for creating targeted drug delivery systems and improving the efficacy of therapeutic agents. Researchers and industry professionals will find this compound indispensable for its efficiency and effectiveness in synthesizing high-purity peptides, which are essential for various biological studies and pharmaceutical applications.

Synonyms
Fmoc-D-Phe(2-CN)-OH, Fmoc-o-Cyano-D-Phe-OH, (R-Fmoc-2-amino-(2-cyanophenyl)propanoic acid
CAS Number
401620-74-4
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD01863770
PubChem ID
3382520
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(2-CN)-OH, Fmoc-o-Cyano-D-Phe-OH, (R-Fmoc-2-amino-(2-cyanophenyl)propanoic acid
CAS Number
401620-74-4
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H20N2O4
Molecular Weight
412.4
MDL Number
MFCD01863770
PubChem ID
3382520
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-cyano-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an important building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its unique structure enables the exploration of new drug candidates, particularly in the development of peptide-based therapeutics targeting specific diseases.
  • Bioconjugation: The presence of the cyano group facilitates bioconjugation reactions, making it useful for attaching peptides to biomolecules, enhancing their stability and functionality.
  • Fluorescent Labeling: The Fmoc group can be easily removed under mild conditions, allowing for the incorporation of fluorescent tags in peptides, which is valuable in biological imaging and tracking.
  • Research in Neuroscience: Its application in studying neuropeptides helps in understanding neuronal signaling pathways, contributing to advancements in neurological research.

Citations