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Catalog Number:
12849
CAS Number:
209252-17-5
Fmoc-L-β-glutamic acid 5-tert-butyl ester
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-L-β-Glu(OtBu)-OH, Fmoc-L-β-homoaspartic acid 5-tert-butyl ester
Documents
$70.50 /100MG
Pack Size Availability Price
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Product Information

Fmoc-L-b-glutamic acid 5-tert-butyl ester is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its tert-butyl ester group enhances solubility and stability, making it an excellent choice for researchers looking to streamline their synthesis processes.

In practical applications, Fmoc-L-b-glutamic acid 5-tert-butyl ester is particularly valuable in the production of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is crucial. Its unique structure allows for efficient coupling reactions, facilitating the creation of complex peptide chains with high purity. Additionally, this compound is beneficial in the development of peptide-based therapeutics, offering researchers a reliable building block for innovative drug design. With its favorable properties and broad applicability, Fmoc-L-b-glutamic acid 5-tert-butyl ester stands out as a key reagent in modern chemical research.

Synonyms
Fmoc-L-β-Glu(OtBu)-OH, Fmoc-L-β-homoaspartic acid 5-tert-butyl ester
CAS Number
209252-17-5
Purity
≥ 95% (HPLC)
Molecular Formula
C24H27NO6
Molecular Weight
425.48
MDL Number
MFCD01862860
PubChem ID
21708967
Appearance
White to off-white powder
Optical Rotation
[a]D25 = 1 ± 3 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Glu(OtBu)-OH, Fmoc-L-β-homoaspartic acid 5-tert-butyl ester
CAS Number
209252-17-5
Purity
≥ 95% (HPLC)
Molecular Formula
C24H27NO6
Molecular Weight
425.48
MDL Number
MFCD01862860
PubChem ID
21708967
Appearance
White to off-white powder
Optical Rotation
[a]D25 = 1 ± 3 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-glutamic acid 5-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing for the efficient assembly of peptides with specific sequences, which are crucial in drug development and biological research.
  • Bioconjugation: Its reactive functional groups enable the attachment of peptides to various biomolecules, facilitating the creation of targeted drug delivery systems and improving therapeutic efficacy.
  • Protein Engineering: Researchers use this compound to modify proteins, enhancing their stability and activity, which is essential in the development of biopharmaceuticals and enzyme applications.
  • Analytical Chemistry: It is employed in the preparation of standards and reagents for chromatographic techniques, aiding in the accurate analysis of complex biological samples.
  • Academic Research: This compound is a valuable tool in academic laboratories for studying protein interactions and functions, contributing to advancements in molecular biology and biochemistry.

Citations