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Catalog Number:
12850
CAS Number:
283160-18-9
Nβ-Fmoc-L-β-glutamine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-β-L-Gln-OH, (S-3-(Fmoc-amino)pentanoic acid 5-amide, Nβ-Fmoc-L-β-homoasparagine
Documents
$100.05 /100MG
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Product Information

Nb-Fmoc-L-b-glutamine is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis, ensuring high purity and yield. Its unique structure not only enhances stability but also allows for easy removal of the Fmoc group under mild conditions, making it an ideal choice for researchers focused on developing complex peptides and proteins.

In addition to its role in peptide synthesis, Nb-Fmoc-L-b-glutamine is also valuable in the pharmaceutical industry for drug development and formulation. Its ability to improve solubility and bioavailability of therapeutic peptides can significantly enhance their efficacy. Researchers in the fields of biochemistry and molecular biology will find this compound particularly useful for studying protein interactions and functions, as well as for developing novel therapeutics. With its exceptional properties and broad applicability, Nb-Fmoc-L-b-glutamine stands out as a crucial tool for advancing scientific research and innovation.

Synonyms
Fmoc-β-L-Gln-OH, (S-3-(Fmoc-amino)pentanoic acid 5-amide, Nβ-Fmoc-L-β-homoasparagine
CAS Number
283160-18-9
Purity
≥ 98% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.39
MDL Number
MFCD01862841
PubChem ID
3383828
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +9.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-β-L-Gln-OH, (S-3-(Fmoc-amino)pentanoic acid 5-amide, Nβ-Fmoc-L-β-homoasparagine
CAS Number
283160-18-9
Purity
≥ 98% (HPLC)
Molecular Formula
C20H20N2O5
Molecular Weight
368.39
MDL Number
MFCD01862841
PubChem ID
3383828
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +9.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nb-Fmoc-L-b-glutamine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for various applications in drug development and biological research.
  • Bioconjugation: Its unique structure enables effective bioconjugation techniques, which are essential for attaching biomolecules to surfaces or other molecules, enhancing the functionality of drugs and diagnostics.
  • Protein Engineering: Researchers use Nb-Fmoc-L-b-glutamine in protein engineering to modify proteins for improved stability and activity, which is crucial in therapeutic applications.
  • Drug Development: The compound is instrumental in the development of new pharmaceuticals, particularly in designing prodrugs that can improve bioavailability and target specific tissues.
  • Research in Neuroscience: It plays a role in neuroscience research by facilitating the study of neurotransmitter pathways, contributing to the understanding of various neurological disorders.

Citations