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Catalog Number:
14055
CAS Number:
105-53-3
Diethyl malonate
Purity:
≥ 99% (Assay)
Synonym(s):
Carbethoxyacetic ester, Methylmalonic acid diethyl ester
Hazmat
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$3,492.93 /200KG
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Product Information

Diethyl malonate is a versatile compound widely utilized in organic synthesis and various industrial applications. This colorless liquid, known for its fruity odor, serves as an important building block in the production of pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure allows for the introduction of various functional groups, making it an essential reagent in the synthesis of complex molecules. Researchers often leverage diethyl malonate in the malonic ester synthesis, which is pivotal for creating a range of biologically active compounds, including barbiturates and other medicinal agents.

Additionally, diethyl malonate is employed in the preparation of esters and as a solvent in various chemical reactions, enhancing its utility in laboratories and industrial settings. Its ability to act as a carbon nucleophile in reactions further expands its application potential, making it a valuable asset for chemists and researchers alike. With its favorable properties and broad applicability, diethyl malonate stands out as a key compound for innovation in chemical synthesis and product development.

Synonyms
Carbethoxyacetic ester, Methylmalonic acid diethyl ester
CAS Number
105-53-3
Purity
≥ 99% (Assay)
Molecular Formula
C7H12O4
Molecular Weight
0
MDL Number
MFCD00009195
PubChem ID
7761
Density
1.06 (Lit.)
Appearance
Colorless liquid
Boiling Point
198 - 200 °C
Conditions
Store at RT
General Information
Synonyms
Carbethoxyacetic ester, Methylmalonic acid diethyl ester
CAS Number
105-53-3
Purity
≥ 99% (Assay)
Molecular Formula
C7H12O4
Molecular Weight
0
MDL Number
MFCD00009195
PubChem ID
7761
Density
1.06 (Lit.)
Appearance
Colorless liquid
Boiling Point
198 - 200 °C
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Diethyl malonate is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: It serves as a key building block in the synthesis of various pharmaceutical compounds, including anti-inflammatory and analgesic drugs, enhancing drug development efficiency.
  • Organic Synthesis: This compound is crucial in the preparation of esters and other derivatives, making it valuable for organic chemists in creating complex molecules.
  • Biochemical Research: Used in metabolic studies, diethyl malonate acts as a competitive inhibitor in certain enzymatic reactions, allowing researchers to explore metabolic pathways effectively.
  • Polymer Production: It is employed in the production of biodegradable polymers, contributing to environmentally friendly materials that reduce plastic waste.
  • Flavor and Fragrance Industry: Diethyl malonate is used as a flavoring agent due to its fruity aroma, making it popular in food and cosmetic formulations.

Citations