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Catalog Number:
14316
CAS Number:
81-25-4
Cholic acid from ox bile
Purity:
≥ 98% (HPLC)
Synonym(s):
Cholalic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
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$35.30 /25G
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Product Information

Cholic acid is a vital bile acid that plays a crucial role in the digestion and absorption of dietary fats. This naturally occurring steroid is recognized for its ability to emulsify fats, facilitating their breakdown and absorption in the intestines. Cholic acid is widely utilized in pharmaceutical formulations, particularly in the development of lipid-based drug delivery systems, where it enhances the solubility and bioavailability of poorly soluble compounds. Its unique structure allows it to interact effectively with cell membranes, making it an essential component in the formulation of various therapeutic agents.

In addition to its applications in pharmaceuticals, cholic acid is also significant in research settings, particularly in studies related to cholesterol metabolism and liver function. Its role as a precursor in the synthesis of other bile acids further underscores its importance in metabolic pathways. Researchers and industry professionals can leverage cholic acid's properties for innovative applications in drug development, nutrition, and biochemistry, making it a versatile compound in both clinical and laboratory environments.

Synonyms
Cholalic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
CAS Number
81-25-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H40O5
Molecular Weight
408.57
MDL Number
MFCD00003672
PubChem ID
303
Melting Point
197 - 202 °C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]D20 = 33 - 39 º
Conditions
Store at RT
General Information
Synonyms
Cholalic acid, 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
CAS Number
81-25-4
Purity
≥ 98% (HPLC)
Molecular Formula
C24H40O5
Molecular Weight
408.57
MDL Number
MFCD00003672
PubChem ID
303
Melting Point
197 - 202 °C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]D20 = 33 - 39 º
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cholic acid is widely utilized in research focused on:

  • Pharmaceutical Development: It serves as a key ingredient in the formulation of bile acid-based drugs, which are used to treat conditions like cholesterol gallstones and certain liver diseases.
  • Nutrition and Dietary Supplements: Cholic acid is important in the formulation of dietary supplements aimed at improving digestion and enhancing nutrient absorption, particularly for individuals with malabsorption issues.
  • Biochemical Research: Researchers use it to study lipid metabolism and the role of bile acids in various metabolic pathways, providing insights into obesity and diabetes.
  • Cosmetic Industry: Its emulsifying properties make it valuable in the formulation of skin care products, helping to improve the texture and absorption of creams and lotions.
  • Analytical Chemistry: Cholic acid is utilized as a standard reference material in chromatography, aiding in the analysis of complex biological samples.

Citations