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Catalog Number:
14350
CAS Number:
149676-40-4
Pefloxacin
Purity:
≥ 99% (Assay)
Synonym(s):
Pefloxacin methanesulfonate, 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylicacid
Antibiotic
Documents
$18.53 /1G
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Product Information

Pefloxacin is a fluoroquinolone antibiotic renowned for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria. This compound is widely utilized in the medical field for treating various infections, including urinary tract infections and respiratory tract infections. Its unique structure, featuring a fluoro group and a piperazine moiety, enhances its potency and bioavailability, making it an effective choice for clinicians. Pefloxacin's mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, crucial enzymes for bacterial replication, which positions it as a vital tool in combating resistant bacterial strains.

In addition to its therapeutic applications, Pefloxacin is also valuable in research settings, particularly in pharmacology and microbiology. Researchers leverage its properties to study antibiotic resistance mechanisms and develop new therapeutic strategies. Its effectiveness against a wide range of pathogens, coupled with its favorable pharmacokinetic profile, makes Pefloxacin a compound of interest for both clinical and laboratory applications. With ongoing studies exploring its potential in various therapeutic areas, Pefloxacin continues to hold promise for future medical advancements.

Synonyms
Pefloxacin methanesulfonate, 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylicacid
CAS Number
149676-40-4
Purity
≥ 99% (Assay)
Molecular Formula
C17H20FN3O3· CH4O3S· 2H2O
Molecular Weight
465.49
MDL Number
MFCD01685696
PubChem ID
6917670
Melting Point
271 °C
Appearance
White or pale yellow crystalline powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Pefloxacin methanesulfonate, 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylicacid
CAS Number
149676-40-4
Purity
≥ 99% (Assay)
Molecular Formula
C17H20FN3O3· CH4O3S· 2H2O
Molecular Weight
465.49
MDL Number
MFCD01685696
PubChem ID
6917670
Melting Point
271 °C
Appearance
White or pale yellow crystalline powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Pefloxacin is widely utilized in research focused on

  • Antibiotic Development: This compound is primarily used as a fluoroquinolone antibiotic, effective against a wide range of bacterial infections, making it crucial in developing new treatments for resistant strains.
  • Clinical Research: Pefloxacin is often studied in clinical trials to evaluate its efficacy and safety in treating conditions like urinary tract infections and respiratory infections, providing valuable data for healthcare professionals.
  • Veterinary Medicine: It is also applied in veterinary settings to treat infections in animals, ensuring the health and productivity of livestock and pets.
  • Pharmaceutical Formulations: Researchers use pefloxacin in formulating new drug delivery systems, enhancing the bioavailability and effectiveness of medications.
  • Microbial Resistance Studies: The compound is instrumental in studies investigating bacterial resistance mechanisms, helping to inform strategies for combating antibiotic resistance in healthcare.

Citations