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Catalog Number:
14355
CAS Number:
81103-11-9
Clarithromycin
Grade:
Meets USP specification
Purity:
96 - 102% (Assay on anhydrous basis)
Documents
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Product Information

Clarithromycin is a semi-synthetic macrolide antibiotic that is widely used in the treatment of various bacterial infections. This compound is particularly effective against respiratory tract infections, skin infections, and certain types of stomach ulcers caused by Helicobacter pylori. Its unique structure allows it to inhibit bacterial protein synthesis, making it a powerful agent in combating resistant strains of bacteria. Clarithromycin is often preferred in clinical settings due to its favorable pharmacokinetic properties, including good oral bioavailability and a relatively long half-life, which allows for less frequent dosing compared to other antibiotics.

In addition to its primary applications in treating infections, Clarithromycin has shown potential in other therapeutic areas, such as the treatment of certain inflammatory conditions and as an adjunct therapy in the management of chronic obstructive pulmonary disease (COPD). Its versatility and effectiveness make it a valuable asset in both hospital and outpatient settings. Researchers and healthcare professionals appreciate its broad spectrum of activity and the ability to target specific pathogens, which enhances treatment outcomes and patient compliance.

CAS Number
81103-11-9
Purity
96 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C38H69NO13
Molecular Weight
747.96
MDL Number
MFCD00865140
PubChem ID
4663848
Melting Point
222 - 227 °C (Lit.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -94 to -102 ° (C=10 mg/mL in Methylene chloride)
Conditions
Store at RT
General Information
CAS Number
81103-11-9
Purity
96 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C38H69NO13
Molecular Weight
747.96
MDL Number
MFCD00865140
PubChem ID
4663848
Melting Point
222 - 227 °C (Lit.)
Appearance
White to off-white crystalline powder
Optical Rotation
[a]D20 = -94 to -102 ° (C=10 mg/mL in Methylene chloride)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Clarithromycin is widely utilized in research focused on:

  • Antibiotic Therapy: It is primarily used to treat various bacterial infections, including respiratory tract infections, skin infections, and Helicobacter pylori eradication, making it essential in clinical settings.
  • Pharmaceutical Development: Researchers use Clarithromycin in the development of new formulations and delivery systems, enhancing its efficacy and patient compliance.
  • Microbial Resistance Studies: It plays a significant role in studying antibiotic resistance mechanisms, helping scientists understand how bacteria adapt and develop resistance to treatment.
  • Combination Therapy Research: Clarithromycin is often studied in combination with other antibiotics to improve treatment outcomes for complex infections, providing insights into synergistic effects.
  • Cardiovascular Research: Emerging studies suggest potential benefits of Clarithromycin in cardiovascular health, particularly in reducing inflammation, which is an area of growing interest in medical research.

Citations