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Catalog Number:
14363
CAS Number:
186350-56-1
Nα-Allyloxycarbonyl-Nε-2-Fmoc-L-lysine
Purity:
99 - 101% (Assay by titration)
Synonym(s):
Aloc-Lys(Fmoc)-OH, Nα-Aloc-Nε-2-Fmoc-L-lysine
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Product Information

Na-Allyloxycarbonyl-Ne-2-Fmoc-L-lysine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to facilitate the formation of peptide bonds while providing stability and protecting functional groups during chemical reactions. Its unique structure, featuring both allyloxycarbonyl and Fmoc protecting groups, allows for selective deprotection, making it an ideal choice for researchers looking to synthesize complex peptides with precision.

In the pharmaceutical and biotechnology industries, Na-Allyloxycarbonyl-Ne-2-Fmoc-L-lysine is utilized in the development of therapeutic peptides, where its properties enhance the efficiency of synthesis processes. Additionally, its application extends to the creation of peptide-based drug candidates, enabling the design of molecules with improved bioavailability and efficacy. Researchers appreciate its compatibility with various coupling reagents and its ability to streamline the synthesis of bioactive compounds, making it a valuable addition to any laboratory focused on peptide chemistry.

Synonyms
Aloc-Lys(Fmoc)-OH, Nα-Aloc-Nε-2-Fmoc-L-lysine
CAS Number
186350-56-1
Purity
99 - 101% (Assay by titration)
Molecular Formula
C25H28N2O6
Molecular Weight
452.5
MDL Number
MFCD09263339
PubChem ID
53396278
Melting Point
119 - 131 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -8 to -10º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Aloc-Lys(Fmoc)-OH, Nα-Aloc-Nε-2-Fmoc-L-lysine
CAS Number
186350-56-1
Purity
99 - 101% (Assay by titration)
Molecular Formula
C25H28N2O6
Molecular Weight
452.5
MDL Number
MFCD09263339
PubChem ID
53396278
Melting Point
119 - 131 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -8 to -10º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Allyloxycarbonyl-Ne-2-Fmoc-L-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of desired products.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, offering a versatile platform for creating novel drugs with improved efficacy and specificity.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Cancer Therapy: It is being explored for its potential applications in cancer therapy, particularly in the design of targeted delivery systems that can improve the effectiveness of chemotherapeutic agents.
  • Protein Engineering: This chemical is valuable in protein engineering, enabling the modification of proteins to enhance their stability and functionality for various industrial applications.

Citations