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Catalog Number:
14407
CAS Number:
161529-14-2
Fmoc-O-tert-butyl-D-β-homoserine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-HomoSer(tBu)-OH
Documents
$93.14 /100MG
Pack Size Availability Price
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Product Information

Fmoc-O-tert-butyl-D-b-homoserine is a valuable compound widely utilized in peptide synthesis and medicinal chemistry. This amino acid derivative features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its tert-butyl group enhances solubility and stability, making it an ideal choice for researchers working on complex peptide sequences. The compound is particularly beneficial in the development of bioactive peptides and pharmaceuticals, where precise control over amino acid functionality is crucial.

In addition to its role in peptide synthesis, Fmoc-O-tert-butyl-D-b-homoserine can be employed in the design of novel therapeutic agents and in the study of protein interactions. Its unique structure allows for the incorporation of D-amino acids into peptides, which can lead to increased resistance to enzymatic degradation and improved pharmacological properties. This compound is a key tool for researchers aiming to innovate in drug development and biomolecular studies, offering a reliable option for enhancing the efficacy and stability of peptide-based therapeutics.

Synonyms
Fmoc-D-β-HomoSer(tBu)-OH
CAS Number
161529-14-2
Purity
≥ 98% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.46
MDL Number
MFCD00235915
Appearance
White powder
Optical Rotation
[a]D20 = -25.4 ± 2 ° (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoSer(tBu)-OH
CAS Number
161529-14-2
Purity
≥ 98% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.46
MDL Number
MFCD00235915
Appearance
White powder
Optical Rotation
[a]D20 = -25.4 ± 2 ° (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-D-b-homoserine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex molecules for drug development and biological studies.
  • Drug Design: Its unique structure allows for the modification of peptide chains, making it valuable in designing new pharmaceuticals that can target specific biological pathways.
  • Biotechnology: In the field of biotechnology, it is used to develop novel biocatalysts and enzymes, enhancing the efficiency of biochemical reactions in industrial processes.
  • Protein Engineering: Researchers leverage its properties to stabilize protein structures, which is crucial for developing therapeutic proteins and vaccines.
  • Analytical Chemistry: This compound is also employed in analytical methods to study protein interactions and modifications, providing insights into cellular mechanisms and disease states.

Citations