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Catalog Number:
14502
CAS Number:
736184-44-4
2-Iodo-D-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
D-Phe(2-I)-OH, o-Iodo-D-phenylalanine, (R-2-Amino-3-(2-iodophenyl)propionic acid
Documents
$68.40 /100MG
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Product Information

2-Iodo-D-phenylalanine is a versatile amino acid derivative that has garnered attention in the fields of medicinal chemistry and biochemistry. This compound, characterized by its unique iodine substitution, plays a crucial role in the synthesis of peptide-based therapeutics and can be utilized in the development of novel drugs targeting various diseases. Its structural similarity to natural amino acids allows for incorporation into peptides, enhancing their biological activity and stability. Researchers have leveraged 2-Iodo-D-phenylalanine in studies related to neuropharmacology and cancer research, where it serves as a valuable tool for probing receptor interactions and enzyme activities.

The compound's unique properties, such as its ability to modulate biological pathways and its potential as a radiolabeled probe, make it an attractive candidate for further exploration in drug discovery and development. Its applications extend to the synthesis of radiopharmaceuticals, where the iodine atom can be used for imaging purposes. With its growing relevance in research and industry, 2-Iodo-D-phenylalanine stands out as a promising compound for those looking to innovate in therapeutic development and biochemical studies.

Synonyms
D-Phe(2-I)-OH, o-Iodo-D-phenylalanine, (R-2-Amino-3-(2-iodophenyl)propionic acid
CAS Number
736184-44-4
Purity
≥ 98% (HPLC)
Molecular Formula
C9H10INO2
Molecular Weight
291.1
MDL Number
MFCD08458534
PubChem ID
3948024
Melting Point
201 - 207 °C (dec.)
Appearance
Off-white powder
Optical Rotation
[α]D25 = -29 ± 2º (C=1 in 0.1N NaOH)
Conditions
Store at 0-8°C
General Information
Synonyms
D-Phe(2-I)-OH, o-Iodo-D-phenylalanine, (R-2-Amino-3-(2-iodophenyl)propionic acid
CAS Number
736184-44-4
Purity
≥ 98% (HPLC)
Molecular Formula
C9H10INO2
Molecular Weight
291.1
MDL Number
MFCD08458534
PubChem ID
3948024
Melting Point
201 - 207 °C (dec.)
Appearance
Off-white powder
Optical Rotation
[α]D25 = -29 ± 2º (C=1 in 0.1N NaOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Iodo-D-phenylalanine is widely utilized in research focused on:

  • Drug Development: This compound serves as a key building block in the synthesis of novel pharmaceuticals, particularly in the development of peptide-based drugs that target specific receptors.
  • Biochemical Research: It is used in studies to investigate protein interactions and enzyme activities, providing insights into metabolic pathways and disease mechanisms.
  • Neuroscience: Researchers employ this compound to explore neurotransmitter systems, aiding in the understanding of neurological disorders and potential treatments.
  • Radiochemistry: The iodine component allows for the incorporation of radioisotopes, making it valuable in imaging techniques such as PET scans for cancer diagnosis.
  • Antibody Production: It is utilized in the design of immunogenic peptides, enhancing the production of specific antibodies for research and therapeutic applications.

Citations