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Catalog Number:
14790
CAS Number:
160347-90-0
Boc-D-pyroglutamic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Pyr-OH, Boc-(R-2-pyrrolidinone-5-carboxylic acid
Documents
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Product Information

Boc-D-pyroglutamic acid is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of pyroglutamic acid offers a stable and effective building block for the development of bioactive peptides, making it invaluable in the fields of medicinal chemistry and drug discovery. Its unique structure, featuring a tert-butoxycarbonyl (Boc) protecting group, enhances its compatibility in various coupling reactions, allowing for the efficient assembly of complex peptide sequences. Researchers appreciate its ability to improve yield and purity in synthetic processes, which can significantly streamline the development of therapeutic agents.

In addition to its role in peptide synthesis, Boc-D-pyroglutamic acid is also explored for its potential applications in the design of enzyme inhibitors and other bioactive molecules. Its stability under a range of conditions and ease of manipulation make it a preferred choice for chemists looking to innovate in drug formulation and delivery systems. With its proven efficacy and broad applicability, Boc-D-pyroglutamic acid stands out as a key compound for professionals aiming to advance their research and product development in the pharmaceutical industry.

Synonyms
Boc-D-Pyr-OH, Boc-(R-2-pyrrolidinone-5-carboxylic acid
CAS Number
160347-90-0
Purity
≥ 98% (HPLC)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD08458561
PubChem ID
12883984
Appearance
White powder
Optical Rotation
[a]D20 = +37º ± 2º (c=1.0 in EtOH)
Conditions
Store at RT
General Information
Synonyms
Boc-D-Pyr-OH, Boc-(R-2-pyrrolidinone-5-carboxylic acid
CAS Number
160347-90-0
Purity
≥ 98% (HPLC)
Molecular Formula
C10H15NO5
Molecular Weight
229.23
MDL Number
MFCD08458561
PubChem ID
12883984
Appearance
White powder
Optical Rotation
[a]D20 = +37º ± 2º (c=1.0 in EtOH)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-pyroglutamic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is particularly beneficial in the pharmaceutical industry for developing new drugs.
  • Drug Development: Its role in modifying amino acids can enhance the stability and bioavailability of therapeutic peptides, making it a valuable asset in the creation of more effective medications.
  • Biotechnology: In the field of biotechnology, Boc-D-pyroglutamic acid is used in the design of enzyme inhibitors and other bioactive compounds, aiding in the development of novel treatments for various diseases.
  • Research Reagents: As a reagent, it is commonly employed in academic and industrial laboratories for studying protein interactions and functions, providing insights into biological processes.
  • Cosmetic Formulations: The compound is also explored in cosmetic chemistry for its potential to enhance skin penetration of active ingredients, improving the efficacy of skincare products.

Citations