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Catalog Number:
14818
Fmoc-2,4-dimethoxy-4'-(carboxymethyloxy)-benzhydrylamine linked to Aminomethyl resin
Synonym(s):
Fmoc rink amide aminomethyl resin
Documents
$65.00 /1G
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Product Information

Fmoc-2,4-dimethoxy-4'-(carboxymethyloxy)-benzhydrylamine linked to Aminomethyl resin is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its structure, characterized by the presence of methoxy and carboxymethyloxy groups, enhances its reactivity and solubility, making it an excellent choice for researchers focused on developing complex peptide sequences.

In practical applications, this compound is particularly valuable in solid-phase peptide synthesis (SPPS), where it facilitates the efficient assembly of peptides on a resin support. Its compatibility with various coupling reagents and its ability to provide high yields make it a preferred choice among chemists. Additionally, the incorporation of the carboxymethyloxy moiety allows for further functionalization, expanding its utility in medicinal chemistry and bioconjugation strategies. Researchers and industry professionals can leverage this compound to streamline their synthesis processes and enhance the efficiency of their peptide-based projects.

Synonyms
Fmoc rink amide aminomethyl resin
Molecular Weight
0.0
MDL Number
MFCD00240214
Appearance
Pale white or slight yellow beads
Substitution
0.6 - 1.0 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
General Information
Synonyms
Fmoc rink amide aminomethyl resin
Molecular Weight
0.0
MDL Number
MFCD00240214
Appearance
Pale white or slight yellow beads
Substitution
0.6 - 1.0 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0 - 8 °C
%DVB
1% DVB
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Properties
Additional property information coming soon!
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Applications

Fmoc-2,4-dimethoxy-4'-(carboxymethyloxy)-benzhydrylamine linked to Aminomethyl resin is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It is used in the development of peptide-based drugs, providing a platform for modifying peptide structures to enhance efficacy and stability.
  • Bioconjugation: The compound facilitates the conjugation of peptides to other biomolecules, aiding in the creation of targeted therapies and diagnostics.
  • Protein Engineering: It plays a role in the modification of proteins, enabling the introduction of functional groups that can alter protein behavior for various applications.
  • Research in Molecular Biology: This chemical is essential for studying protein interactions and functions, contributing to advancements in understanding biological processes.

Citations