🌟 99% Happy customers

📦 Same-day shipping on in-stock items

Catalog Number:
14852
CAS Number:
208174-14-5
Fmoc-L-homoarginine hydrochloride
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Homoarg-OH · HCl, Nα-Fmoc-(S)-2-amino-6-guanidinohexanoic acid hydrochloride
Documents
$65.00 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-L-homoarginine hydrochloride is a versatile amino acid derivative widely utilized in peptide synthesis and bioconjugation applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a homoarginine side chain, enhances its utility in the development of bioactive peptides and therapeutic agents. Researchers in the fields of medicinal chemistry and biochemistry often leverage Fmoc-L-homoarginine hydrochloride for its ability to introduce cationic properties into peptides, which can improve their binding affinity and biological activity.

This compound is particularly valuable in the synthesis of peptides that require specific functional groups for enhanced interaction with biological targets. Its application extends to the development of peptide-based drugs, where the incorporation of homoarginine can lead to improved pharmacokinetic properties. Additionally, Fmoc-L-homoarginine hydrochloride is used in the preparation of peptide libraries for drug discovery, enabling researchers to explore a wide range of biological activities. With its robust performance in peptide synthesis, this compound stands out as a preferred choice for professionals seeking to innovate in the realm of peptide therapeutics.

Synonyms
Fmoc-L-Homoarg-OH · HCl, Nα-Fmoc-(S)-2-amino-6-guanidinohexanoic acid hydrochloride
CAS Number
208174-14-5
Purity
≥ 99% (HPLC)
Molecular Formula
C22H26N4O4 · HCl
Molecular Weight
446.97
MDL Number
MFCD07357322
PubChem ID
5141096
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Homoarg-OH · HCl, Nα-Fmoc-(S)-2-amino-6-guanidinohexanoic acid hydrochloride
CAS Number
208174-14-5
Purity
≥ 99% (HPLC)
Molecular Formula
C22H26N4O4 · HCl
Molecular Weight
446.97
MDL Number
MFCD07357322
PubChem ID
5141096
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-homoarginine hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of complex peptide sequences.
  • Drug Development: Its unique structure allows for the incorporation of homoarginine into peptide-based drugs, potentially improving their bioactivity and therapeutic profiles in treating various diseases.
  • Bioconjugation: Researchers use it to create bioconjugates, linking peptides to other molecules like drugs or imaging agents, which can enhance targeting and efficacy in drug delivery systems.
  • Protein Engineering: The compound is valuable in modifying proteins to improve their stability and function, making it essential in biotechnology and pharmaceutical research.
  • Diagnostics: Its application in the development of diagnostic tools, such as biosensors, helps in the detection of specific biomolecules, facilitating early disease diagnosis and monitoring.

Citations