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Catalog Number:
15040
CAS Number:
917099-00-4
Fmoc-4,5-dehydro-D-Leucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-4,5-dehydro-D-Leu-OH
Documents
$134.70 /100MG
Pack Size Availability Price
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Product Information

Fmoc-4,5-dehydro-D-Leucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique structure that enhances its stability and reactivity, making it an ideal choice for researchers focused on creating complex peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing excellent protection during synthesis. This property is particularly beneficial in the development of peptide-based therapeutics, where precision and stability are paramount.

In addition to its applications in peptide synthesis, Fmoc-4,5-dehydro-D-Leucine has shown potential in the design of novel bioactive compounds and as a building block in the creation of cyclic peptides. Its ability to facilitate the formation of specific conformations can lead to improved biological activity and selectivity in drug candidates. Researchers in medicinal chemistry and biochemistry will find this compound invaluable for advancing their projects, particularly in the fields of drug discovery and development.

Synonyms
Fmoc-4,5-dehydro-D-Leu-OH
CAS Number
917099-00-4
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD04112681
PubChem ID
4712546
Appearance
White powder
Optical Rotation
[a]D20 = +19 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-4,5-dehydro-D-Leu-OH
CAS Number
917099-00-4
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD04112681
PubChem ID
4712546
Appearance
White powder
Optical Rotation
[a]D20 = +19 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4,5-dehydro-D-Leucine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex structures with high purity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing novel therapeutics, especially those targeting specific biological pathways.
  • Protein Engineering: Researchers use this compound to modify proteins, enhancing their stability and activity, which is crucial in biotechnological applications.
  • Bioconjugation: Fmoc-4,5-dehydro-D-Leucine is employed in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and drug delivery systems.
  • Research in Cancer Therapeutics: Its application in designing peptide-based inhibitors has shown promise in cancer research, providing a pathway for developing targeted therapies with fewer side effects.

Citations