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Catalog Number:
15056
CAS Number:
206060-40-4
Fmoc-3-methoxy-L-phenlyalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-L-Phe(3-OMe)-OH, Fmoc-3-methoxy-L-Phe-OH, (S-Fmoc-2-amino-3-(3-methoxyphenyl)propionic acid
Documents
$88.63 /250MG
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Product Information

Fmoc-3-methoxy-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during solid-phase peptide synthesis. Its unique structure, characterized by the methoxy substitution on the phenyl ring, enhances the compound's solubility and stability, making it an ideal choice for researchers looking to create complex peptides with improved bioactivity.

In practical applications, Fmoc-3-methoxy-L-phenylalanine is particularly valuable in the pharmaceutical industry for the synthesis of peptide-based therapeutics and in the development of novel drug candidates. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups allows for the efficient assembly of biologically active peptides. Researchers appreciate its compatibility with various coupling reagents and its role in enhancing the yield and purity of synthesized peptides, ultimately contributing to more effective drug discovery processes.

Synonyms
Fmoc-L-Phe(3-OMe)-OH, Fmoc-3-methoxy-L-Phe-OH, (S-Fmoc-2-amino-3-(3-methoxyphenyl)propionic acid
CAS Number
206060-40-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD01317009
PubChem ID
4712578
Melting Point
152 - 155 °C
Appearance
White to off-white solid
Optical Rotation
[a]20D = 32 ± 1 ° (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Phe(3-OMe)-OH, Fmoc-3-methoxy-L-Phe-OH, (S-Fmoc-2-amino-3-(3-methoxyphenyl)propionic acid
CAS Number
206060-40-4
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD01317009
PubChem ID
4712578
Melting Point
152 - 155 °C
Appearance
White to off-white solid
Optical Rotation
[a]20D = 32 ± 1 ° (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-methoxy-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This chemical serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide chains with high purity and yield.
  • Drug Development: It is used in the pharmaceutical industry for developing peptide-based drugs, which can target specific biological pathways, offering potential treatments for various diseases.
  • Bioconjugation: The compound is valuable in bioconjugation processes, where it can be attached to biomolecules, enhancing their stability and functionality for applications in diagnostics and therapeutics.
  • Research in Neuroscience: Researchers utilize this chemical to study neuropeptides, contributing to a better understanding of neurological functions and potential treatments for neurodegenerative diseases.
  • Custom Peptide Libraries: It plays a crucial role in the creation of custom peptide libraries for high-throughput screening, facilitating drug discovery and development by allowing researchers to test numerous peptide variants efficiently.

Citations