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Catalog Number:
15110
CAS Number:
478183-65-2
Fmoc-2-iodo-D-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Phe(2-I)-OH, Fmoc-o-iodo-D-Phe-OH, (R-Fmoc-2-amino-3-(2-iodophenyl)propionic acid
Documents
$168.35 /1G
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Product Information

Fmoc-2-iodo-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of an iodine atom on the phenyl ring, enhances its reactivity and allows for the introduction of various functional groups, making it an invaluable tool in medicinal chemistry and biochemistry. Researchers often leverage Fmoc-2-iodo-D-phenylalanine in the development of peptide-based therapeutics, where its ability to facilitate the formation of complex peptide structures is essential.

In addition to its role in peptide synthesis, this compound is also significant in the study of protein interactions and the design of novel biomolecules. Its unique properties enable researchers to explore new avenues in drug discovery and development, particularly in targeting specific biological pathways. With its robust applications in both academic and industrial settings, Fmoc-2-iodo-D-phenylalanine stands out as a key compound for professionals seeking to innovate in the fields of pharmaceuticals and biotechnology.

Synonyms
Fmoc-D-Phe(2-I)-OH, Fmoc-o-iodo-D-Phe-OH, (R-Fmoc-2-amino-3-(2-iodophenyl)propionic acid
CAS Number
478183-65-2
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20INO4
Molecular Weight
513.4
MDL Number
MFCD06796745
PubChem ID
53427492
Melting Point
132-138 °C
Optical Rotation
[a]D = +68 ± 2º (C=1 in DMF
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-Phe(2-I)-OH, Fmoc-o-iodo-D-Phe-OH, (R-Fmoc-2-amino-3-(2-iodophenyl)propionic acid
CAS Number
478183-65-2
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20INO4
Molecular Weight
513.4
MDL Number
MFCD06796745
PubChem ID
53427492
Melting Point
132-138 °C
Optical Rotation
[a]D = +68 ± 2º (C=1 in DMF
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-2-iodo-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it useful in the development of novel pharmaceuticals, especially those targeting specific biological pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: The iodine atom in its structure facilitates bioconjugation processes, enabling researchers to attach biomolecules to surfaces or other compounds for targeted delivery in therapeutic applications.
  • Research in Cancer Therapy: This compound is being explored for its potential in cancer research, particularly in the development of targeted therapies that can selectively attack cancer cells.
  • Analytical Chemistry: Fmoc-2-iodo-D-phenylalanine can be used in analytical methods to study protein interactions and folding, providing insights into protein behavior in various environments.

Citations