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Catalog Number:
15124
CAS Number:
478183-62-9
Fmoc-β-cyclobutyl-L-alanine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-Ala(β-cyclobutyl)-OH
Documents
$134.70 /250MG
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Product Information

Fmoc-b-cyclobutyl-L-alanine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound, characterized by its unique cyclobutyl side chain and the protective Fmoc (9-fluorenylmethoxycarbonyl) group, is particularly valuable in solid-phase peptide synthesis (SPPS). Its structure enhances the stability and solubility of peptides, making it an excellent choice for researchers looking to develop novel therapeutic peptides. The cyclobutyl moiety contributes to the compound's ability to adopt specific conformations, which can be beneficial in designing peptides with improved biological activity.

In addition to its applications in peptide synthesis, Fmoc-b-cyclobutyl-L-alanine is also utilized in the development of peptidomimetics and other bioactive compounds. Its unique properties allow for the exploration of new drug candidates with enhanced efficacy and reduced side effects. Researchers in medicinal chemistry and biochemistry will find this compound particularly useful for creating innovative solutions in drug design and development, making it a valuable addition to any laboratory focused on peptide research.

Synonyms
Fmoc-Ala(β-cyclobutyl)-OH
CAS Number
478183-62-9
Purity
≥ 97% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.43
MDL Number
MFCD03840400
PubChem ID
4712593
Appearance
Pale white or White to off-white solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-Ala(β-cyclobutyl)-OH
CAS Number
478183-62-9
Purity
≥ 97% (HPLC)
Molecular Formula
C22H23NO4
Molecular Weight
365.43
MDL Number
MFCD03840400
PubChem ID
4712593
Appearance
Pale white or White to off-white solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-b-cyclobutyl-L-alanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with enhanced stability.
  • Drug Development: Its unique cyclobutyl side chain can influence the biological activity of peptides, making it valuable in the pharmaceutical industry for developing new therapeutic agents.
  • Bioconjugation: The Fmoc protecting group allows for selective reactions, facilitating the attachment of peptides to various biomolecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: This compound is used in studies aimed at modifying protein structures, enabling researchers to explore new functionalities and improve protein stability.
  • Analytical Chemistry: It can be employed in the development of analytical methods for characterizing peptides, providing insights into their structure and function.

Citations