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Catalog Number:
15165
CAS Number:
89786-04-9
Tazobactam (Free acid)
Purity:
≥ 99% (HPLC)
Synonym(s):
(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
Antibiotic
Documents
$36.65 /1G
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Product Information

Tazobactam (Free acid) is a potent β-lactamase inhibitor that plays a crucial role in enhancing the efficacy of β-lactam antibiotics against resistant bacterial strains. This compound is particularly valuable in the pharmaceutical industry, where it is used to combat infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa and Escherichia coli. By inhibiting the enzymes that bacteria produce to resist antibiotics, Tazobactam allows for a broader spectrum of activity for penicillins and cephalosporins, making it an essential component in combination therapies.

Researchers and healthcare professionals appreciate Tazobactam for its ability to restore the effectiveness of existing antibiotics, thereby reducing the need for developing new drugs. Its unique structure and properties enable it to effectively penetrate bacterial membranes, providing an advantage over other β-lactamase inhibitors. This compound is widely utilized in clinical settings and is integral to the formulation of various combination antibiotics, enhancing treatment outcomes for patients with serious infections.

Synonyms
(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number
89786-04-9
Purity
≥ 99% (HPLC)
Molecular Formula
C10H12N4O5S
Molecular Weight
300.29
MDL Number
MFCD00867002
PubChem ID
4836
Appearance
White to off-white solid
Optical Rotation
+127 to + 139 º
Conditions
Store at 0-8°C
General Information
Synonyms
(2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-1-ylmethyl-4lambda6-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
CAS Number
89786-04-9
Purity
≥ 99% (HPLC)
Molecular Formula
C10H12N4O5S
Molecular Weight
300.29
MDL Number
MFCD00867002
PubChem ID
4836
Appearance
White to off-white solid
Optical Rotation
+127 to + 139 º
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Tazobactam (Free acid) is widely utilized in research focused on:

  • Antibiotic Development: It serves as a crucial component in the formulation of beta-lactamase inhibitors, enhancing the efficacy of antibiotics against resistant bacterial strains.
  • Pharmaceutical Formulations: Commonly used in combination with other antibiotics, it helps to extend the spectrum of activity and improve treatment outcomes in infections.
  • Clinical Research: Tazobactam is frequently studied in clinical trials to assess its effectiveness in treating various infections, providing valuable data for healthcare professionals.
  • Microbiology Labs: Used in laboratory settings to test bacterial resistance patterns, aiding researchers in understanding and combating antibiotic resistance.
  • Veterinary Medicine: Its application extends to veterinary formulations, helping to treat infections in animals, thus improving animal health and welfare.

Citations