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Catalog Number:
15174
CAS Number:
78348-28-4
Nicotinic acid hydroxysuccinimidyl ester
Synonym(s):
Nicotinyl OSu
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Product Information

Nicotinic acid hydroxysuccinimidyl ester is a versatile compound widely utilized in bioconjugation and drug delivery applications. This ester serves as an effective linker in the formation of stable conjugates, making it invaluable in the development of targeted therapeutics and diagnostic agents. Its ability to react with amines allows for the attachment of various biomolecules, including peptides and proteins, facilitating the creation of complex molecular structures essential for modern biomedical research.

Researchers appreciate its unique properties, such as high stability and solubility, which enhance its performance in diverse experimental conditions. Additionally, nicotinic acid hydroxysuccinimidyl ester is recognized for its potential in vaccine development, where it can be employed to improve immunogenicity through effective antigen presentation. Its applications extend to the fields of proteomics and metabolomics, where it aids in the analysis of protein interactions and modifications. This compound stands out for its efficiency in creating robust bioconjugates, making it a preferred choice for professionals seeking reliable and effective solutions in their research endeavors.

Synonyms
Nicotinyl OSu
CAS Number
78348-28-4
Molecular Formula
C10H8N2O4
Molecular Weight
220.18
MDL Number
MFCD00619111
PubChem ID
870586
Conditions
Store at 0-8°C
General Information
Synonyms
Nicotinyl OSu
CAS Number
78348-28-4
Molecular Formula
C10H8N2O4
Molecular Weight
220.18
MDL Number
MFCD00619111
PubChem ID
870586
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nicotinic acid hydroxysuccinimidyl ester is widely utilized in research focused on:

  • Bioconjugation: This compound serves as a versatile linker in bioconjugation processes, allowing researchers to attach biomolecules, such as proteins or antibodies, to surfaces or other molecules, enhancing the development of targeted therapies.
  • Drug Delivery Systems: Its ability to form stable conjugates makes it valuable in creating drug delivery systems that improve the efficacy and specificity of therapeutic agents, particularly in cancer treatment.
  • Diagnostics: It is used in the development of diagnostic tools, such as biosensors, where it helps in the immobilization of biomolecules, increasing the sensitivity and accuracy of detection methods.
  • Vaccine Development: The compound plays a role in vaccine formulation by facilitating the conjugation of antigens to carrier proteins, which can enhance immune responses and improve vaccine effectiveness.
  • Research Reagents: As a reagent in chemical biology, it aids in the study of protein interactions and cellular processes, providing insights that can lead to advancements in drug discovery and development.

Citations