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Catalog Number:
15255
CAS Number:
220497-67-6
(-)-(1R,3S)-N-Fmoc-3-aminocyclopentane carboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
(-)-(1R,3S)-N-Fmoc-β-homocycloleucine
Documents
$140.90 /250MG
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Product Information

(-)-(1R,3S)-N-Fmoc-3-aminocyclopentane carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focused on developing novel therapeutic peptides. The compound's cyclopentane backbone enhances its conformational flexibility, which can be advantageous in optimizing peptide interactions with biological targets.

In addition to its role in peptide synthesis, (-)-(1R,3S)-N-Fmoc-3-aminocyclopentane carboxylic acid is also valuable in the development of drug candidates, particularly in the design of cyclic peptides and peptidomimetics. Its ability to facilitate the formation of stable structures can lead to improved pharmacological properties. Researchers in the pharmaceutical industry will find this compound particularly beneficial for its potential to enhance bioavailability and target specificity in drug design.

Synonyms
(-)-(1R,3S)-N-Fmoc-β-homocycloleucine
CAS Number
220497-67-6
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01311758
PubChem ID
2734463
Appearance
White powder
Optical Rotation
[a]D20 = -14.5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
(-)-(1R,3S)-N-Fmoc-β-homocycloleucine
CAS Number
220497-67-6
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01311758
PubChem ID
2734463
Appearance
White powder
Optical Rotation
[a]D20 = -14.5 ± 2 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(-)-(1R,3S)-N-Fmoc-3-aminocyclopentane carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and diverse peptide structures.
  • Drug Development: It is employed in medicinal chemistry for the development of novel pharmaceuticals, especially those targeting specific biological pathways, enhancing efficacy and selectivity in drug design.
  • Bioconjugation: The compound is useful in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: It plays a role in neuroscience research by acting as a scaffold for the development of compounds that can modulate neurotransmitter systems, potentially leading to new treatments for neurological disorders.
  • Custom Synthesis: This chemical is often utilized in custom synthesis projects, providing researchers with the flexibility to create tailored compounds for specific applications in various fields, including materials science and biochemistry.

Citations