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Catalog Number:
15295
CAS Number:
269398-84-7
Fmoc-3-methyl-D-β-homophenylalanine
Purity:
≥ 99%
Synonym(s):
Fmoc-D-β-HomoPhe(3-Me)-OH, Fmoc-(R-3-amino-4-(3-methylphenyl)butyric acid
Documents
$79.22 /100MG
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Product Information

Fmoc-3-methyl-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by a 3-methylphenyl side chain, enhances the hydrophobic interactions in peptide sequences, making it particularly valuable in the design of bioactive peptides and pharmaceuticals. Researchers appreciate its ability to improve the stability and solubility of peptides, which is crucial for effective drug formulation and delivery.

In practical applications, Fmoc-3-methyl-D-b-homophenylalanine is employed in solid-phase peptide synthesis (SPPS), enabling the efficient assembly of complex peptide chains. Its use in combinatorial chemistry and high-throughput screening allows for the rapid exploration of peptide libraries, facilitating the discovery of novel therapeutic agents. Additionally, this compound's favorable properties make it an excellent choice for the development of peptide-based vaccines and targeted therapies, underscoring its significance in modern medicinal chemistry.

Synonyms
Fmoc-D-β-HomoPhe(3-Me)-OH, Fmoc-(R-3-amino-4-(3-methylphenyl)butyric acid
CAS Number
269398-84-7
Purity
≥ 99%
Molecular Formula
C26H25NO4
Molecular Weight
415.49
MDL Number
MFCD01860926
PubChem ID
53397952
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-HomoPhe(3-Me)-OH, Fmoc-(R-3-amino-4-(3-methylphenyl)butyric acid
CAS Number
269398-84-7
Purity
≥ 99%
Molecular Formula
C26H25NO4
Molecular Weight
415.49
MDL Number
MFCD01860926
PubChem ID
53397952
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3-methyl-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, due to its protective Fmoc group that allows for selective deprotection.
  • Drug Development: It is used in the development of peptide-based therapeutics, providing researchers with a means to create novel compounds that can target specific biological pathways.
  • Bioconjugation: The chemical is valuable in bioconjugation processes, where it helps attach peptides to other biomolecules, enhancing the delivery and efficacy of drugs.
  • Research in Neuroscience: Its application in studying neuropeptides aids in understanding neurological functions and disorders, making it significant for researchers in neuroscience.
  • Custom Peptide Libraries: The compound is instrumental in creating diverse peptide libraries for screening potential drug candidates, allowing for high-throughput analysis in pharmaceutical research.

Citations