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Catalog Number:
15305
CAS Number:
269398-94-9
Fmoc-pentafluoro-D-β-homophenylalanine
Purity:
≥ 98%
Synonym(s):
Fmoc-D-β-HomoPhe(F)5-OH, Fmoc-(R-3-amino-4-(pentafluorophenyl)butyric acid
Documents
$92.10 /100MG
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Product Information

Fmoc-pentafluoro-D-b-homophenylalanine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is characterized by its unique pentafluorophenyl group, which enhances the stability and bioactivity of peptides. Researchers and industry professionals utilize Fmoc-pentafluoro-D-b-homophenylalanine for its ability to improve the solubility and selectivity of peptide-based therapeutics, making it an invaluable tool in medicinal chemistry. Its distinctive fluorinated structure allows for greater manipulation during synthesis, enabling the creation of more complex and effective peptide sequences.

In practical applications, this compound is particularly beneficial in the development of targeted therapies and in the study of protein interactions. Its use in solid-phase peptide synthesis (SPPS) facilitates the efficient assembly of peptides with enhanced pharmacological properties. Additionally, the incorporation of Fmoc-pentafluoro-D-b-homophenylalanine into peptide libraries can lead to the discovery of novel compounds with potential therapeutic applications. With its unique properties and versatility, this amino acid derivative is essential for advancing research in biochemistry and pharmaceutical sciences.

Synonyms
Fmoc-D-β-HomoPhe(F)5-OH, Fmoc-(R-3-amino-4-(pentafluorophenyl)butyric acid
CAS Number
269398-94-9
Purity
≥ 98%
Molecular Formula
C25H18F5NO4
Molecular Weight
491.41
MDL Number
MFCD01860941
PubChem ID
53397959
Appearance
White powder
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-HomoPhe(F)5-OH, Fmoc-(R-3-amino-4-(pentafluorophenyl)butyric acid
CAS Number
269398-94-9
Purity
≥ 98%
Molecular Formula
C25H18F5NO4
Molecular Weight
491.41
MDL Number
MFCD01860941
PubChem ID
53397959
Appearance
White powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-pentafluoro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, where its protective Fmoc group allows for selective deprotection and coupling.
  • Drug Development: Its unique fluorinated structure enhances the pharmacokinetic properties of peptides, making it valuable in the design of novel therapeutics with improved efficacy and stability.
  • Bioconjugation: The compound can be used to create bioconjugates for targeted drug delivery systems, leveraging its ability to form stable linkages with various biomolecules.
  • Fluorine-Containing Compounds: Its incorporation into drug candidates can improve their metabolic stability and bioavailability, making it a preferred choice in medicinal chemistry.
  • Research in Protein Engineering: This chemical is instrumental in the development of modified proteins with enhanced properties, aiding researchers in studying protein interactions and functions.

Citations