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Catalog Number:
15332
CAS Number:
270062-83-4
Fmoc-4-fluoro-L-β-homophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPhe(4-F)-OH, Fmoc-(S)-3-amino-4-(4-fluorophenyl)butyric acid
Documents
$80.30 /100MG
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Product Information

Fmoc-4-fluoro-L-b-homophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorinated phenyl group, enhancing its bioactivity and stability, making it an ideal choice for researchers focused on developing novel therapeutics. Its unique structure allows for improved interactions in biological systems, which is particularly beneficial in the design of peptide-based drugs.

In practical applications, Fmoc-4-fluoro-L-b-homophenylalanine serves as a key building block in the synthesis of peptides with specific pharmacological properties. Its incorporation into peptide sequences can lead to enhanced potency and selectivity, making it a preferred choice in medicinal chemistry and biochemistry. Researchers appreciate its ease of use in solid-phase peptide synthesis, where the Fmoc protecting group allows for straightforward deprotection and coupling reactions. This compound not only streamlines the synthesis process but also contributes to the development of innovative therapeutic agents.

Synonyms
Fmoc-L-β-HomoPhe(4-F)-OH, Fmoc-(S)-3-amino-4-(4-fluorophenyl)butyric acid
CAS Number
270062-83-4
Purity
≥ 99% (HPLC)
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD01861013
PubChem ID
53396103
Appearance
White solid
Optical Rotation
[a]D25 = -6.5 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoPhe(4-F)-OH, Fmoc-(S)-3-amino-4-(4-fluorophenyl)butyric acid
CAS Number
270062-83-4
Purity
≥ 99% (HPLC)
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD01861013
PubChem ID
53396103
Appearance
White solid
Optical Rotation
[a]D25 = -6.5 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-fluoro-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures for various applications in drug development.
  • Drug Design: Its unique fluorinated structure enhances the pharmacokinetic properties of peptide drugs, making it valuable in the pharmaceutical industry for designing more effective therapeutics.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other compounds, facilitating the development of targeted drug delivery systems.
  • Research in Protein Engineering: It plays a significant role in protein engineering studies, helping scientists modify proteins to improve their stability and functionality for various biotechnological applications.
  • Analytical Chemistry: Fmoc-4-fluoro-L-b-homophenylalanine is utilized in analytical methods to study protein interactions and behaviors, providing insights that are crucial for both academic and industrial research.

Citations