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Catalog Number:
15335
CAS Number:
270062-86-7
Fmoc-4-bromo-L-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPhe(4-Br)-OH, Fmoc-(S)-3-amino-4-(4-bromophenyl)butyric acid
Documents
$72.31 /100MG
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Product Information

Fmoc-4-bromo-L-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of amino groups during the synthesis process. Its bromine substitution on the phenyl ring enhances its reactivity, making it an excellent choice for introducing specific functionalities into peptide chains. Researchers and industry professionals appreciate its role in the development of peptide-based therapeutics, particularly in the fields of oncology and neurology, where precise modifications can lead to improved bioactivity and selectivity.

This compound is particularly beneficial for solid-phase peptide synthesis (SPPS), allowing for streamlined processes and higher yields. Its stability under various reaction conditions and compatibility with a range of coupling reagents make it a preferred choice among chemists. Additionally, Fmoc-4-bromo-L-b-homophenylalanine can be utilized in the design of novel biomaterials and drug delivery systems, showcasing its potential in advancing pharmaceutical research and development.

Synonyms
Fmoc-L-β-HomoPhe(4-Br)-OH, Fmoc-(S)-3-amino-4-(4-bromophenyl)butyric acid
CAS Number
270062-86-7
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22BrNO4
Molecular Weight
480.36
MDL Number
MFCD01861016
PubChem ID
53397992
Appearance
White powder
Optical Rotation
[a]D25 = -18.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-β-HomoPhe(4-Br)-OH, Fmoc-(S)-3-amino-4-(4-bromophenyl)butyric acid
CAS Number
270062-86-7
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22BrNO4
Molecular Weight
480.36
MDL Number
MFCD01861016
PubChem ID
53397992
Appearance
White powder
Optical Rotation
[a]D25 = -18.5 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-bromo-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific biological pathways, due to its unique side chain properties.
  • Bioconjugation: Researchers use it for bioconjugation applications, linking peptides to other molecules such as antibodies or drugs, enhancing the efficacy of therapeutic agents.
  • Research in Neuroscience: The compound is valuable in neuroscience research, where it aids in the study of neuropeptides and their functions, contributing to the understanding of neurological disorders.
  • Material Science: In material science, it is utilized in the development of novel materials with specific properties, such as improved biocompatibility for biomedical applications.

Citations