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Catalog Number:
15364
CAS Number:
270063-52-0
Fmoc-3,4-dichloro-L-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(S-3-amino-4-(3,4-dichlorophenyl)butyric acid
Documents
$100.05 /100MG
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Product Information

Fmoc-3,4-dichloro-L-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of dichlorophenyl and a homophenylalanine backbone, enhances its reactivity and stability, making it an ideal choice for researchers focused on developing complex peptide sequences.

In the pharmaceutical industry, Fmoc-3,4-dichloro-L-b-homophenylalanine is particularly valuable for the synthesis of bioactive peptides, which can be used in therapeutic applications ranging from cancer treatment to antimicrobial agents. Its ability to facilitate the introduction of specific functional groups allows for the fine-tuning of peptide properties, thereby improving efficacy and reducing side effects. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, making it a preferred choice for those looking to innovate in peptide chemistry.

Synonyms
Fmoc-L-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(S-3-amino-4-(3,4-dichlorophenyl)butyric acid
CAS Number
270063-52-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01861048
PubChem ID
53397932
Appearance
White powder
Optical Rotation
[α]D20 = -21.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-HomoPhe(3,4-DiCl)-OH, Fmoc-(S-3-amino-4-(3,4-dichlorophenyl)butyric acid
CAS Number
270063-52-0
Purity
≥ 98% (HPLC)
Molecular Formula
C25H21Cl2NO4
Molecular Weight
470.35
MDL Number
MFCD01861048
PubChem ID
53397932
Appearance
White powder
Optical Rotation
[α]D20 = -21.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-3,4-dichloro-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide structures efficiently.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially those targeting specific proteins, enhancing the efficacy of therapeutic agents.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach drugs or labels to biomolecules, facilitating targeted delivery systems in cancer therapy.
  • Research in Neuroscience: Its applications extend to neuroscience, where it aids in studying neurotransmitter interactions and the development of neuroprotective agents.
  • Protein Engineering: This compound is valuable in protein engineering, enabling the modification of proteins to improve their stability and functionality for various industrial applications.

Citations