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Catalog Number:
15417
CAS Number:
270596-43-5
Fmoc-4-chloro-L-β-homophenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPhe(4-Cl)-OH, Fmoc-(S-3-amino-4-(4-chlorophenyl)butyric acid
Documents
$79.22 /100MG
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Product Information

Fmoc-4-chloro-L-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which enhances its stability and compatibility in solid-phase peptide synthesis (SPPS). The presence of the 4-chloro substitution on the phenyl ring provides additional reactivity, making it an excellent choice for researchers looking to introduce specific functionalities into peptides. Its structural characteristics allow for the incorporation of this amino acid into various peptide sequences, facilitating the exploration of novel therapeutic agents and biomolecules.

In practical applications, Fmoc-4-chloro-L-b-homophenylalanine is particularly valuable in the development of peptide-based drugs, where precise modifications can lead to improved efficacy and selectivity. Researchers in medicinal chemistry and biochemistry can leverage this compound to create peptides with enhanced biological activity or tailored properties for specific applications. Its ability to undergo further chemical transformations makes it a preferred choice for professionals seeking to innovate in peptide design and synthesis.

Synonyms
Fmoc-L-β-HomoPhe(4-Cl)-OH, Fmoc-(S-3-amino-4-(4-chlorophenyl)butyric acid
CAS Number
270596-43-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22ClNO4
Molecular Weight
435.91
MDL Number
MFCD01861002
PubChem ID
44181917
Appearance
White powder
Optical Rotation
[a]D25 = -19.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-HomoPhe(4-Cl)-OH, Fmoc-(S-3-amino-4-(4-chlorophenyl)butyric acid
CAS Number
270596-43-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H22ClNO4
Molecular Weight
435.91
MDL Number
MFCD01861002
PubChem ID
44181917
Appearance
White powder
Optical Rotation
[a]D25 = -19.0 ± 2º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-chloro-L-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide sequences efficiently.
  • Drug Development: It plays a significant role in the development of pharmaceuticals, especially in designing peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to other biomolecules, improving the delivery and effectiveness of therapeutic agents.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research for their potential to modulate neurotransmitter systems, contributing to the understanding of neurological disorders.
  • Custom Peptide Libraries: Researchers utilize it to create custom peptide libraries for high-throughput screening, facilitating the discovery of new bioactive compounds.

Citations