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Catalog Number:
15422
CAS Number:
270596-48-0
Fmoc-L-β-homopropargylglycine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-β-HomoPra-OH, Fmoc-(S)-3-amino-5-hexynoic acid
Documents
$75.00 /25MG
Pack Size Availability Price
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Product Information

Fmoc-L-b-homopropargylglycine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is characterized by its unique structure, which includes a fluorenylmethoxycarbonyl (Fmoc) protecting group that facilitates the selective modification of amino acids during the synthesis process. Its alkyne functionality allows for click chemistry applications, making it an invaluable tool for researchers in the fields of medicinal chemistry and bioconjugation.

This compound is particularly useful in the development of peptide-based therapeutics, where it can enhance the stability and bioactivity of peptides. Additionally, its ability to participate in various coupling reactions opens up possibilities for creating complex molecular architectures. Researchers can leverage Fmoc-L-b-homopropargylglycine in the design of novel biomaterials and drug delivery systems, highlighting its significance in advancing pharmaceutical research and development.

Synonyms
Fmoc-L-β-HomoPra-OH, Fmoc-(S)-3-amino-5-hexynoic acid
CAS Number
270596-48-0
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19NO4
Molecular Weight
349.39
MDL Number
MFCD01861008
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 21 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-HomoPra-OH, Fmoc-(S)-3-amino-5-hexynoic acid
CAS Number
270596-48-0
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19NO4
Molecular Weight
349.39
MDL Number
MFCD01861008
Appearance
White to off-white solid
Optical Rotation
[a]D20 = 21 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-b-homopropargylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in the development of novel therapeutics and drug candidates.
  • Bioconjugation: Its unique alkyne functional group allows for efficient bioconjugation reactions, enabling researchers to attach various biomolecules for targeted drug delivery systems.
  • Fluorescent Labeling: The Fmoc protecting group facilitates the introduction of fluorescent tags, which are essential for tracking and imaging in biological studies.
  • Research in Neuroscience: This compound is used to study neuropeptides and their roles in neurological functions, providing insights into potential treatments for neurological disorders.
  • Custom Drug Development: Its versatility in modifying peptide structures makes it valuable for pharmaceutical companies aiming to create customized drugs with specific properties.

Citations