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Catalog Number:
15439
CAS Number:
374791-04-5
Fmoc-(R-3-amino-3-(3-nitrophenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(3-NO2)-OH, (R-Fmoc-3-nitro-β-phenylalanine
Documents
$72.31 /250MG
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Product Information

Fmoc-(R)-3-amino-3-(3-nitrophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (fluorenylmethyloxycarbonyl) protecting group, which facilitates the selective protection of amino groups during the synthesis of complex peptides. Its chiral nature, indicated by the (R) configuration, enhances its relevance in the production of enantiomerically pure compounds, making it an essential tool for researchers focused on developing pharmaceuticals with specific biological activities.

The incorporation of the 3-nitrophenyl moiety not only contributes to the compound's stability but also allows for the introduction of functional groups through further chemical modifications. This property is particularly beneficial in medicinal chemistry, where fine-tuning the structure of drug candidates is crucial. Fmoc-(R)-3-amino-3-(3-nitrophenyl)propionic acid is ideal for applications in peptide libraries, combinatorial chemistry, and the synthesis of biologically active compounds, providing researchers with a reliable and efficient option for their synthetic needs.

Synonyms
Fmoc-D-β-Phe(3-NO2)-OH, (R-Fmoc-3-nitro-β-phenylalanine
CAS Number
374791-04-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD01631080
PubChem ID
17830545
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +25 ± 2º (C=1% in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(3-NO2)-OH, (R-Fmoc-3-nitro-β-phenylalanine
CAS Number
374791-04-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD01631080
PubChem ID
17830545
Appearance
White to off-white powder
Optical Rotation
[a]D25 = +25 ± 2º (C=1% in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3-nitrophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors or enzymes, enhancing efficacy and selectivity.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, facilitating the development of targeted therapies and diagnostics.
  • Research in Neuroscience: Given its structural similarity to neurotransmitters, it is employed in neuroscience research to study receptor interactions and signal transduction pathways, aiding in the understanding of neurological disorders.
  • Fluorescent Labeling: The nitrophenyl group allows for fluorescent labeling, making it useful in various imaging techniques in biological research, helping visualize cellular processes in real-time.

Citations