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Catalog Number:
15511
CAS Number:
331763-70-3
Fmoc-4-fluoro-D-β-homophenylalanine
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-b-HomoPhe(4-F)-OH, Fmoc-(R)-3-amino-4-(4-fluorophenyl)butyric acid
Documents
$86.23 /100MG
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Product Information

Fmoc-4-fluoro-D-b-homophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its structural characteristics, including the presence of a fluorine atom, enhance its reactivity and stability, making it an excellent choice for researchers aiming to develop novel peptides with improved pharmacological properties.

In the pharmaceutical industry, Fmoc-4-fluoro-D-b-homophenylalanine is particularly advantageous for the synthesis of bioactive peptides, which can serve as potential therapeutics in treating various diseases. Its ability to introduce fluorine into peptide sequences allows for the exploration of new biological activities and enhances the overall efficacy of the resulting compounds. Researchers appreciate its compatibility with standard coupling reagents and its ease of use, which streamlines the synthesis process while ensuring high yields and purity.

Synonyms
Fmoc-D-b-HomoPhe(4-F)-OH, Fmoc-(R)-3-amino-4-(4-fluorophenyl)butyric acid
CAS Number
331763-70-3
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD01860915
PubChem ID
53396103
Appearance
White powder
Conditions
Store at 0-8°
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
General Information
Synonyms
Fmoc-D-b-HomoPhe(4-F)-OH, Fmoc-(R)-3-amino-4-(4-fluorophenyl)butyric acid
CAS Number
331763-70-3
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD01860915
PubChem ID
53396103
Appearance
White powder
Conditions
Store at 0-8°
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Properties
Additional property information coming soon!
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Applications

Fmoc-4-fluoro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with enhanced stability.
  • Drug Development: Its unique properties make it useful in the development of pharmaceuticals, especially in designing peptide-based drugs that target specific biological pathways.
  • Bioconjugation: The chemical can be employed in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted therapies and diagnostics.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is used in studies exploring receptor interactions and signaling pathways in the nervous system.
  • Fluorine Chemistry: The presence of fluorine enhances the compound's bioactivity and metabolic stability, making it a subject of interest in fluorine chemistry research, which can lead to the development of more effective therapeutic agents.

Citations