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Catalog Number:
15523
CAS Number:
332064-67-2
Fmoc-(R-2-tetrahydroisoquinoline acetic acid
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-D-Tqa-OH, Fmoc-(R-1,2,3,4-tetrahydroisoquinoline-3-acetic acid
Documents
$106.96 /100MG
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Product Information

Fmoc-(R)-2-tetrahydroisoquinoline acetic acid is a versatile compound widely utilized in the field of organic synthesis and medicinal chemistry. This compound serves as a valuable building block in the development of peptide-based therapeutics and drug discovery, particularly due to its unique structural features that enhance the stability and bioactivity of peptides. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection, making it an ideal choice for researchers looking to synthesize complex peptide sequences with precision.

In addition to its applications in peptide synthesis, Fmoc-(R)-2-tetrahydroisoquinoline acetic acid has shown promise in the development of novel pharmaceuticals targeting various biological pathways. Its ability to facilitate the introduction of isoquinoline moieties into drug candidates can lead to enhanced pharmacological profiles. Researchers in the pharmaceutical industry can leverage this compound to streamline their synthesis processes and improve the efficacy of their drug formulations, making it a crucial addition to any medicinal chemistry toolkit.

Synonyms
Fmoc-D-Tqa-OH, Fmoc-(R-1,2,3,4-tetrahydroisoquinoline-3-acetic acid
CAS Number
332064-67-2
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C26H23NO4
Molecular Weight
413.47
MDL Number
MFCD01860934
PubChem ID
53397993
Melting Point
60-66 °C
Appearance
White powder
Optical Rotation
[a]D20 = -33.4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Tqa-OH, Fmoc-(R-1,2,3,4-tetrahydroisoquinoline-3-acetic acid
CAS Number
332064-67-2
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C26H23NO4
Molecular Weight
413.47
MDL Number
MFCD01860934
PubChem ID
53397993
Melting Point
60-66 °C
Appearance
White powder
Optical Rotation
[a]D20 = -33.4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-2-tetrahydroisoquinoline acetic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique structure is beneficial in the development of pharmaceuticals, particularly in creating compounds that target specific biological pathways, enhancing efficacy and reducing side effects.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules for therapeutic applications, which is crucial in the development of targeted drug delivery systems.
  • Research in Neuroscience: Its derivatives are explored in neuroscience research, particularly in studying neurotransmitter systems, which can lead to advancements in treatments for neurological disorders.
  • Material Science: The compound is also being investigated for its potential applications in creating novel materials with specific properties, such as improved biocompatibility for medical devices.

Citations