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Catalog Number:
15527
CAS Number:
332064-91-2
Boc-D-β-homopropargylglycine
Purity:
≥ 98%
Synonym(s):
Boc-D-β-HomoPra-OH, Boc-(R-3-amino-5-hexynoic acid
Documents
$86.23 /25MG
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Product Information

Boc-D-b-homopropargylglycine is a versatile amino acid derivative that plays a significant role in peptide synthesis and medicinal chemistry. This compound is recognized for its unique propargyl group, which facilitates the introduction of bioactive functionalities into peptides, making it an invaluable tool for researchers in drug development and biochemical studies. Its Boc (tert-butyloxycarbonyl) protecting group enhances stability and solubility, allowing for easier handling and manipulation during synthesis.

In practical applications, Boc-D-b-homopropargylglycine is utilized in the design of peptide-based therapeutics and can serve as a building block for the development of inhibitors targeting various biological pathways. Its ability to participate in click chemistry reactions further expands its utility in creating complex molecular architectures. Researchers appreciate its compatibility with standard coupling reagents, making it an efficient choice for peptide synthesis. With its unique properties and broad applicability, Boc-D-b-homopropargylglycine stands out as a crucial component in the toolkit of modern chemical synthesis and drug discovery.

Synonyms
Boc-D-β-HomoPra-OH, Boc-(R-3-amino-5-hexynoic acid
CAS Number
332064-91-2
Purity
≥ 98%
Molecular Formula
C11H17NO4
Molecular Weight
227.26
MDL Number
MFCD01860909
PubChem ID
53398007
Melting Point
87 - 93 °C
Appearance
White powder
Optical Rotation
[a]D25 = -23 ± 2 º (C=1 in EtOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-D-β-HomoPra-OH, Boc-(R-3-amino-5-hexynoic acid
CAS Number
332064-91-2
Purity
≥ 98%
Molecular Formula
C11H17NO4
Molecular Weight
227.26
MDL Number
MFCD01860909
PubChem ID
53398007
Melting Point
87 - 93 °C
Appearance
White powder
Optical Rotation
[a]D25 = -23 ± 2 º (C=1 in EtOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-b-homopropargylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs and therapeutics.
  • Bioconjugation: Its unique alkyne functional group allows for efficient bioconjugation techniques, enabling researchers to attach biomolecules for targeted drug delivery systems.
  • Protein Labeling: The compound is used in labeling proteins for studies in cellular biology, helping to track protein interactions and localization within cells.
  • Research in Neuroscience: It plays a role in studying neurotransmitter systems, particularly in the development of potential treatments for neurological disorders.
  • Drug Development: The compound's properties make it a candidate for creating novel therapeutic agents, especially in oncology and infectious disease research.

Citations