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Catalog Number:
15582
CAS Number:
507472-20-0
Fmoc-(S)-3-amino-3-(3-trifluoromethylphenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(3-CF3)-OH, (S)-Fmoc-3-trifluoromethyl-β-phenylalanine
Documents
$35.30 /100MG
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Product Information

Fmoc-(S)-3-amino-3-(3-trifluoromethylphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique trifluoromethyl group, which enhances its biological activity and stability, making it particularly valuable in medicinal chemistry. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, facilitating the synthesis of complex peptides with high purity and yield. Researchers and industry professionals appreciate its application in the design of peptide-based therapeutics, where precise amino acid sequences are crucial for efficacy.

In addition to its role in peptide synthesis, this compound can be employed in the development of novel materials and as a reagent in various organic transformations. Its distinctive properties enable the exploration of new chemical pathways and the creation of innovative compounds. With its robust performance and adaptability, Fmoc-(S)-3-amino-3-(3-trifluoromethylphenyl)propionic acid stands out as an essential tool for researchers aiming to push the boundaries of peptide chemistry and drug discovery.

Synonyms
Fmoc-L-β-Phe(3-CF3)-OH, (S)-Fmoc-3-trifluoromethyl-β-phenylalanine
CAS Number
507472-20-0
Purity
≥ 99% (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428002
PubChem ID
24902252
Appearance
White solid
Optical Rotation
[a]D20 = -16.5 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Phe(3-CF3)-OH, (S)-Fmoc-3-trifluoromethyl-β-phenylalanine
CAS Number
507472-20-0
Purity
≥ 99% (HPLC)
Molecular Formula
C25H20F3NO4
Molecular Weight
455.43
MDL Number
MFCD03428002
PubChem ID
24902252
Appearance
White solid
Optical Rotation
[a]D20 = -16.5 ± 2 ° (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(3-trifluoromethylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures with high purity and yield.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of peptides, making it valuable in the development of new therapeutic agents that may exhibit improved efficacy and selectivity.
  • Bioconjugation: The compound can be used in bioconjugation techniques, facilitating the attachment of peptides to various biomolecules, which is essential for creating targeted drug delivery systems.
  • Research in Neuroscience: It plays a role in the design of neuropeptides, which are crucial for understanding and treating neurological disorders, thereby contributing to advancements in neuroscience research.
  • Analytical Chemistry: The compound is utilized in analytical methods for characterizing peptide structures, helping researchers ensure the accuracy and reliability of their findings in various studies.

Citations