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Catalog Number:
15593
CAS Number:
517905-91-8
Fmoc-(R)-3-amino-3-(3-cyanophenyl)propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(3-CN)-OH, (R)-Fmoc-3-cyano-β-phenylalanine
Documents
$206.60 /1G
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Product Information

Fmoc-(R)-3-amino-3-(3-cyanophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of amino groups during the synthesis of peptides. Its structure, characterized by the presence of a cyanophenyl group, enhances its utility in the development of bioactive compounds, particularly in the design of inhibitors and pharmaceuticals targeting specific biological pathways.

Researchers and industry professionals appreciate this compound for its ability to improve the solubility and stability of peptides, making it an ideal choice for applications in drug discovery and development. Additionally, its chiral nature allows for the synthesis of enantiomerically pure compounds, which is crucial in the pharmaceutical industry to ensure efficacy and safety. With its robust performance in peptide coupling reactions, Fmoc-(R)-3-amino-3-(3-cyanophenyl)propionic acid stands out as a valuable asset in the toolkit of chemists focused on innovative therapeutic solutions.

Synonyms
Fmoc-D-β-Phe(3-CN)-OH, (R)-Fmoc-3-cyano-β-phenylalanine
CAS Number
517905-91-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H20N2O4
Molecular Weight
412.44
MDL Number
MFCD03428043
PubChem ID
24902253
Melting Point
198 - 200 °C
Appearance
Off-white powder
Optical Rotation
[a]D25 = +27 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(3-CN)-OH, (R)-Fmoc-3-cyano-β-phenylalanine
CAS Number
517905-91-8
Purity
≥ 99% (HPLC)
Molecular Formula
C25H20N2O4
Molecular Weight
412.44
MDL Number
MFCD03428043
PubChem ID
24902253
Melting Point
198 - 200 °C
Appearance
Off-white powder
Optical Rotation
[a]D25 = +27 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3-cyanophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing researchers to create complex peptide structures efficiently.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing new drugs, especially those targeting specific receptors or pathways due to its ability to modify peptide sequences.
  • Bioconjugation: The compound is used in bioconjugation processes, facilitating the attachment of peptides to other biomolecules, which is essential for creating targeted therapies and diagnostic agents.
  • Research in Neuroscience: It plays a role in studying neuropeptides, helping researchers understand their functions and potential therapeutic applications in neurological disorders.
  • Material Science: The compound can be utilized in the development of novel materials with specific properties, such as enhanced biocompatibility for medical devices or drug delivery systems.

Citations