Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
15605
CAS Number:
517905-93-0
Fmoc-(R)-3-amino-3-(2-nitrophenyl)propionic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(2-NO2)-OH, (R)-Fmoc-2-nitro-β-phenylalanine
Documents
$83.42 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-(R)-3-amino-3-(2-nitrophenyl)propionic acid is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the presence of a nitrophenyl group, enhances its reactivity and allows for the introduction of specific functionalities in peptide chains, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

This compound is particularly beneficial in the development of peptide-based therapeutics, where precise control over amino acid sequences is crucial. Its application extends to the synthesis of bioactive peptides, which are important in drug discovery and development. Additionally, Fmoc-(R)-3-amino-3-(2-nitrophenyl)propionic acid can be employed in the creation of peptide libraries for high-throughput screening, facilitating the identification of novel compounds with therapeutic potential. With its reliable performance and compatibility with various coupling reagents, this amino acid derivative stands out as a preferred choice for professionals seeking efficiency and precision in peptide synthesis.

Synonyms
Fmoc-D-β-Phe(2-NO2)-OH, (R)-Fmoc-2-nitro-β-phenylalanine
CAS Number
517905-93-0
Purity
≥ 95% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD03428045
PubChem ID
6915691
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -123 ± 3 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-Phe(2-NO2)-OH, (R)-Fmoc-2-nitro-β-phenylalanine
CAS Number
517905-93-0
Purity
≥ 95% (HPLC)
Molecular Formula
C24H20N2O6
Molecular Weight
432.43
MDL Number
MFCD03428045
PubChem ID
6915691
Appearance
White to off-white solid
Optical Rotation
[a]D20 = -123 ± 3 º (C=1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2-nitrophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it valuable in the design of novel pharmaceuticals, especially in targeting specific biological pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules such as proteins and antibodies to therapeutic agents, improving targeted delivery in medical applications.
  • Research in Neuroscience: Due to its structural properties, it is employed in studies related to neurotransmitter pathways, aiding in the understanding of neurological disorders and potential treatments.
  • Fluorescent Labeling: The nitrophenyl group allows for fluorescent labeling, making it useful in various imaging techniques in biological research, enhancing visualization of cellular processes.

Citations