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Catalog Number:
15628
CAS Number:
501015-27-6
Fmoc-(S)-3-amino-3-(3-methylphenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-Phe(3-Me)-OH, (S)-Fmoc-3-methyl-β-phenylalanine
Documents
$50.30 /100MG
Pack Size Availability Price
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Product Information

Fmoc-(S)-3-amino-3-(3-methylphenyl)propionic acid is a versatile building block in peptide synthesis, particularly valued for its role in the development of peptide-based therapeutics and research applications. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis process. Its unique structure allows for the introduction of a chiral center, making it an excellent choice for researchers focused on creating enantiomerically pure compounds.

In practical applications, Fmoc-(S)-3-amino-3-(3-methylphenyl)propionic acid is utilized in the synthesis of bioactive peptides, which can serve as potential drug candidates in various therapeutic areas, including oncology and neurology. Its stability and compatibility with standard coupling reagents make it a preferred choice among chemists for solid-phase peptide synthesis. By incorporating this compound into their workflows, researchers can enhance the efficiency and effectiveness of their peptide synthesis projects, ultimately leading to the discovery of novel therapeutic agents.

Synonyms
Fmoc-L-β-Phe(3-Me)-OH, (S)-Fmoc-3-methyl-β-phenylalanine
CAS Number
501015-27-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427972
PubChem ID
22831637
Appearance
White powder
Optical Rotation
[a]D25 = -20 to -22 ° (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-β-Phe(3-Me)-OH, (S)-Fmoc-3-methyl-β-phenylalanine
CAS Number
501015-27-6
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO4
Molecular Weight
401.46
MDL Number
MFCD03427972
PubChem ID
22831637
Appearance
White powder
Optical Rotation
[a]D25 = -20 to -22 ° (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(S)-3-amino-3-(3-methylphenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis. Its protective Fmoc group allows for selective deprotection, facilitating the assembly of complex peptide structures.
  • Drug Development: Researchers in pharmaceutical industries use this compound to create novel therapeutic agents. Its unique structure can enhance the bioactivity of drug candidates, making it valuable in the development of new medications.
  • Bioconjugation: The compound is employed in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules. This is particularly useful in creating targeted drug delivery systems and diagnostic tools.
  • Material Science: In the field of material science, it is used to modify polymer properties. By incorporating this compound, researchers can tailor materials for specific applications, such as improved mechanical strength or thermal stability.
  • Research in Neuroscience: Its application extends to neuroscience, where it aids in the study of neurotransmitter systems. The compound can be used to create analogs that help researchers understand receptor interactions and signaling pathways.

Citations