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Catalog Number:
15641
CAS Number:
511272-32-5
Fmoc-(R-3-amino-3-(3-methoxyphenyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-D-β-Phe(3-OMe)-OH, (R-Fmoc-3-methoxy-β-phenylalanine
Documents
$65.40 /100MG
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Product Information

Fmoc-(R)-3-amino-3-(3-methoxyphenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure, characterized by the presence of a methoxyphenyl group, enhances its solubility and stability, making it an ideal choice for researchers looking to develop complex peptide sequences.

In the pharmaceutical industry, this compound plays a crucial role in the design of bioactive peptides and drug candidates, particularly in the development of therapeutics targeting various diseases. Its ability to facilitate the incorporation of non-natural amino acids into peptide chains allows for the exploration of novel therapeutic avenues. Additionally, Fmoc-(R)-3-amino-3-(3-methoxyphenyl)propionic acid stands out for its compatibility with automated peptide synthesizers, streamlining the synthesis process and improving efficiency in research laboratories.

Synonyms
Fmoc-D-β-Phe(3-OMe)-OH, (R-Fmoc-3-methoxy-β-phenylalanine
CAS Number
511272-32-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD03428013
PubChem ID
2759197
Melting Point
134-140 °C
Appearance
White powder
Optical Rotation
[a]D25 = +28 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-β-Phe(3-OMe)-OH, (R-Fmoc-3-methoxy-β-phenylalanine
CAS Number
511272-32-5
Purity
≥ 98% (HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.46
MDL Number
MFCD03428013
PubChem ID
2759197
Melting Point
134-140 °C
Appearance
White powder
Optical Rotation
[a]D25 = +28 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(3-methoxyphenyl)propionic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides that can be used in drug development.
  • Drug Development: Its unique structure aids in the design of novel therapeutic agents, especially in areas like cancer and neurodegenerative diseases, providing researchers with a versatile tool for creating targeted treatments.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules to drugs or imaging agents, enhancing the specificity and efficacy of therapeutic applications.
  • Research in Neuroscience: Due to its structural properties, it is employed in studies related to neuroactive compounds, helping researchers understand the interactions between peptides and neurotransmitter systems.
  • Analytical Chemistry: It can be utilized as a standard in analytical methods, aiding in the quantification and characterization of similar compounds in various samples, ensuring accuracy in research findings.

Citations