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Catalog Number:
15672
CAS Number:
511272-38-1
Fmoc-(R-3-amino-3-(2,3-dichlorophenyl)propionic acid
Synonym(s):
Fmoc-D-β-Phe(2,3-DiCl)-OH, (R-Fmoc-2,3-dichloro-β-phenylalanine
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Product Information

Fmoc-(R)-3-amino-3-(2,3-dichlorophenyl)propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by the presence of a 2,3-dichlorophenyl moiety, enhances its reactivity and allows for the introduction of diverse functionalities, making it an invaluable tool for researchers in medicinal chemistry and biochemistry.

In practical applications, Fmoc-(R)-3-amino-3-(2,3-dichlorophenyl)propionic acid has been employed in the design of bioactive peptides and pharmaceuticals, particularly in the development of compounds targeting specific biological pathways. Its ability to facilitate the synthesis of complex peptide sequences positions it as a preferred choice for professionals seeking to innovate in drug discovery and development. With its reliable performance and compatibility with various coupling reagents, this compound stands out as a key ingredient for advancing research in peptide-based therapeutics.

Synonyms
Fmoc-D-β-Phe(2,3-DiCl)-OH, (R-Fmoc-2,3-dichloro-β-phenylalanine
CAS Number
511272-38-1
Molecular Formula
C24H19Cl2NO4
Molecular Weight
456.32
MDL Number
MFCD03428019
PubChem ID
2759188
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-β-Phe(2,3-DiCl)-OH, (R-Fmoc-2,3-dichloro-β-phenylalanine
CAS Number
511272-38-1
Molecular Formula
C24H19Cl2NO4
Molecular Weight
456.32
MDL Number
MFCD03428019
PubChem ID
2759188
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2,3-dichlorophenyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a crucial building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptide structures efficiently.
  • Drug Development: Its unique structure makes it valuable in the pharmaceutical industry for developing novel drugs, especially those targeting specific biological pathways influenced by amino acids.
  • Bioconjugation: The chemical is often used in bioconjugation processes, where it helps link biomolecules to therapeutic agents, enhancing the efficacy of drug delivery systems.
  • Research in Neuroscience: This compound is utilized in studies related to neurobiology, where it can help in understanding the role of amino acids in neurotransmitter function and behavior.
  • Analytical Chemistry: It is employed in analytical methods for characterizing and quantifying amino acids and peptides, providing researchers with reliable data for their studies.

Citations