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Catalog Number:
15697
CAS Number:
511272-45-0
Fmoc-(R)-3-amino-3-(2-thienyl)propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-β-Ala-(2-thienyl)-OH, (R)-Fmoc-2-thienyl-β-phenylalanine
Documents
$83.32 /100MG
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Product Information

Fmoc-(R)-3-amino-3-(2-thienyl)propionic acid is a valuable building block in peptide synthesis, particularly favored for its ability to introduce thienyl side chains into peptides. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which allows for selective deprotection under mild conditions, making it an ideal choice for researchers focused on synthesizing complex peptides with enhanced stability and bioactivity. Its unique thienyl moiety contributes to the compound's potential in developing novel therapeutic agents, especially in the fields of medicinal chemistry and drug discovery.

Researchers and industry professionals can leverage Fmoc-(R)-3-amino-3-(2-thienyl)propionic acid in the design of peptides that exhibit improved pharmacological properties, such as increased solubility and binding affinity. Its application extends to the development of peptide-based drugs and biomaterials, where the incorporation of thienyl groups can enhance the overall efficacy of the resulting compounds. This makes it a crucial component for those looking to innovate in peptide therapeutics and related applications.

Synonyms
Fmoc-L-β-Ala-(2-thienyl)-OH, (R)-Fmoc-2-thienyl-β-phenylalanine
CAS Number
511272-45-0
Purity
≥ 98% (HPLC)
Molecular Formula
C22H19NO4S
Molecular Weight
393.46
MDL Number
MFCD03428026
PubChem ID
24902259
Melting Point
181 - 187 °C
Appearance
White powder
Optical Rotation
[a]D25 = 39 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-β-Ala-(2-thienyl)-OH, (R)-Fmoc-2-thienyl-β-phenylalanine
CAS Number
511272-45-0
Purity
≥ 98% (HPLC)
Molecular Formula
C22H19NO4S
Molecular Weight
393.46
MDL Number
MFCD03428026
PubChem ID
24902259
Melting Point
181 - 187 °C
Appearance
White powder
Optical Rotation
[a]D25 = 39 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-3-amino-3-(2-thienyl)propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids while preventing unwanted reactions. This is crucial in developing complex peptides for pharmaceuticals.
  • Drug Development: Its unique structure contributes to the design of novel drug candidates, particularly in the field of neuropharmacology, where compounds targeting specific receptors can lead to better therapeutic outcomes.
  • Bioconjugation: The compound can be used in bioconjugation processes, linking biomolecules to create targeted drug delivery systems, enhancing the efficacy of treatments while minimizing side effects.
  • Research in Neuroscience: It is valuable in studying the interactions between neurotransmitters and receptors, providing insights into neurological disorders and potential treatments.
  • Material Science: The compound's properties make it suitable for developing functional materials, such as sensors and coatings, that respond to environmental stimuli, opening avenues in advanced material applications.

Citations