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Catalog Number:
16184
CAS Number:
596797-14-7
Nα-Fmoc-Nγ-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-D-2,4-diaminobutyric acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Dab(Dde)-OH
Documents
$67.34 /250MG
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Product Information

Na-Fmoc-Ng-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-D-2,4-diaminobutyric acid is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by a cyclohexenylidene moiety, enhances its reactivity and stability, making it an ideal choice for researchers focused on developing complex peptide sequences.

In addition to its role in peptide synthesis, this compound can be employed in the design of novel therapeutics, particularly in the fields of oncology and neurology, where targeted drug delivery is crucial. The incorporation of the 4,4-dimethyl-2,6-dioxocyclohex-1-ylidene group provides additional functionalization opportunities, allowing for the exploration of diverse biological activities. Researchers will appreciate its potential for creating innovative compounds with improved efficacy and specificity in therapeutic applications.

Synonyms
Fmoc-D-Dab(Dde)-OH
CAS Number
596797-14-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H32N2O6
Molecular Weight
504.6
MDL Number
MFCD09265180
PubChem ID
137317221
Melting Point
135-150 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -24 ± 2º (C=1 in CHCl3
Conditions
Store at 0-8°C
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
General Information
Synonyms
Fmoc-D-Dab(Dde)-OH
CAS Number
596797-14-7
Purity
≥ 99% (HPLC)
Molecular Formula
C29H32N2O6
Molecular Weight
504.6
MDL Number
MFCD09265180
PubChem ID
137317221
Melting Point
135-150 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = -24 ± 2º (C=1 in CHCl3
Conditions
Store at 0-8°C
Safety & Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Properties
Additional property information coming soon!
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Applications

Na-Fmoc-Ng-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-D-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, enhancing the efficiency and selectivity of the process, which is crucial for developing therapeutic peptides.
  • Drug Development: It plays a significant role in the design of novel drug candidates, particularly in the field of oncology, by modifying amino acid sequences to improve bioactivity and reduce side effects.
  • Bioconjugation: The compound is employed in bioconjugation techniques, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential for creating targeted drug delivery systems.
  • Research in Protein Engineering: It is used in the modification of proteins to study their structure-function relationships, aiding in the development of more effective enzymes and antibodies.
  • Material Science: This chemical is also explored in the development of advanced materials, particularly in creating functional polymers that can respond to environmental stimuli.

Citations