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Catalog Number:
16186
CAS Number:
1217645-10-7
Nα-Bis-Fmoc-D-2,4-diaminobutyric acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Dab(Fmoc)-OH
Documents
$86.23 /250MG
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Product Information

Na,g-Bis-Fmoc-D-2,4-diaminobutyric acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features two Fmoc (9-fluorenylmethyloxycarbonyl) protecting groups, which facilitate the selective protection of amine functionalities during the synthesis of complex peptides. Its unique structure allows for enhanced stability and solubility, making it an ideal choice for researchers engaged in the development of therapeutic peptides and other bioactive compounds.

In the pharmaceutical industry, Na,g-Bis-Fmoc-D-2,4-diaminobutyric acid is particularly valuable for its role in the synthesis of peptide-based drugs, where precise control over amino acid sequences is crucial. Its application extends to the development of targeted therapies, including those for cancer and metabolic disorders. Researchers appreciate its ability to streamline the synthesis process while maintaining high yields and purity, ultimately leading to more efficient drug development workflows.

Synonyms
Fmoc-D-Dab(Fmoc)-OH
CAS Number
1217645-10-7
Purity
≥ 99% (HPLC)
Molecular Formula
C34H30N2O6
Molecular Weight
562.6
MDL Number
MFCD02094099
PubChem ID
68662008
Melting Point
183-190 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +8 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Dab(Fmoc)-OH
CAS Number
1217645-10-7
Purity
≥ 99% (HPLC)
Molecular Formula
C34H30N2O6
Molecular Weight
562.6
MDL Number
MFCD02094099
PubChem ID
68662008
Melting Point
183-190 °C
Appearance
White crystalline powder
Optical Rotation
[a]D20 = +8 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na,g-Bis-Fmoc-D-2,4-diaminobutyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a significant role in medicinal chemistry for developing new pharmaceuticals, particularly those targeting specific receptors or pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: The chemical is used in bioconjugation processes, facilitating the attachment of biomolecules to drugs or imaging agents, which is crucial for targeted therapy and diagnostics.
  • Research in Cancer Therapy: Its applications extend to cancer research, where it aids in the design of targeted therapies that can selectively attack cancer cells, improving treatment outcomes.
  • Material Science: This compound is also explored in the development of novel materials, such as hydrogels and nanomaterials, which have applications in drug delivery systems and tissue engineering.

Citations