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Catalog Number:
16536
CAS Number:
203866-13-1
Boc-cis-4-fluoro-L-proline
Purity:
≥ 97% (HPLC)
Synonym(s):
Boc-cis-4-fluoro-L-Pro-OH, (2S,4S)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid
Documents
$22.03 /1G
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Product Information

Boc-cis-4-fluoro-L-proline is a valuable building block in the synthesis of peptides and pharmaceuticals, particularly in the development of biologically active compounds. This compound features a unique fluorine substitution that enhances its stability and bioactivity, making it an ideal candidate for researchers focused on drug design and development. Its Boc (tert-butyloxycarbonyl) protecting group allows for easy manipulation during synthetic procedures, facilitating the incorporation of this amino acid into complex molecular architectures.

In the pharmaceutical industry, Boc-cis-4-fluoro-L-proline has been utilized in the synthesis of various peptide-based therapeutics, particularly those targeting neurological disorders and cancer. Its distinct properties enable researchers to explore novel therapeutic pathways, providing a competitive edge in drug discovery. With its excellent solubility and compatibility with various coupling reagents, this compound is a preferred choice for chemists aiming to streamline their synthetic processes while achieving high yields.

Synonyms
Boc-cis-4-fluoro-L-Pro-OH, (2S,4S)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid
CAS Number
203866-13-1
Purity
≥ 97% (HPLC)
Molecular Formula
C10H16FNO4
Molecular Weight
233.24
MDL Number
MFCD04973957
PubChem ID
4712523
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-cis-4-fluoro-L-Pro-OH, (2S,4S)-Boc-4-fluoro-pyrrolidine-2-carboxylic acid
CAS Number
203866-13-1
Purity
≥ 97% (HPLC)
Molecular Formula
C10H16FNO4
Molecular Weight
233.24
MDL Number
MFCD04973957
PubChem ID
4712523
Appearance
White to off-white solid
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-cis-4-fluoro-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs, enhancing their stability and bioactivity.
  • Drug Development: Its unique fluorinated structure can improve the pharmacological properties of drug candidates, making it a key component in medicinal chemistry for creating more effective therapeutics.
  • Biotechnology: In the field of biotechnology, it is used to modify proteins, allowing researchers to explore new functionalities and improve the performance of biopharmaceuticals.
  • Research on Protein Folding: This compound aids in studying protein folding and stability, providing insights that can lead to advancements in understanding diseases related to protein misfolding.
  • Material Science: Boc-cis-4-fluoro-L-proline is also explored in the development of novel materials, particularly in creating polymers with enhanced properties for various industrial applications.

Citations