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Catalog Number:
16539
CAS Number:
203866-17-5
Boc-4,4-Difluoro-L-proline methyl ester
Purity:
≥ 99% (NMR)
Documents
$132.20 /250MG
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Product Information

Boc-4,4-Difluoro-L-proline methyl ester is a versatile compound widely utilized in the fields of medicinal chemistry and pharmaceutical research. This compound, known for its unique difluorinated proline structure, serves as a valuable building block in the synthesis of various bioactive molecules, particularly in the development of peptide-based therapeutics. Its distinctive properties, including enhanced stability and bioavailability, make it an attractive choice for researchers aiming to optimize drug design and efficacy.

In addition to its applications in drug development, Boc-4,4-Difluoro-L-proline methyl ester is also employed in the synthesis of fluorinated amino acids, which have shown promise in improving the pharmacokinetic profiles of therapeutic agents. The incorporation of fluorine atoms can significantly influence the biological activity and metabolic stability of compounds, making this ester a key player in the advancement of innovative treatments. Researchers and industry professionals can leverage its unique characteristics to explore new avenues in drug discovery and development, ultimately contributing to the creation of more effective therapeutic solutions.

CAS Number
203866-17-5
Purity
≥ 99% (NMR)
Molecular Formula
C11H17F2NO4
Molecular Weight
265.25
MDL Number
MFCD03094918
PubChem ID
53401926
Melting Point
40-45 °C
Appearance
White solid
Optical Rotation
[α]D23 = -53 ± 3º (C=1.01% in MeOH)
Conditions
Store at 0-8 °C
General Information
CAS Number
203866-17-5
Purity
≥ 99% (NMR)
Molecular Formula
C11H17F2NO4
Molecular Weight
265.25
MDL Number
MFCD03094918
PubChem ID
53401926
Melting Point
40-45 °C
Appearance
White solid
Optical Rotation
[α]D23 = -53 ± 3º (C=1.01% in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4,4-Difluoro-L-proline methyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of novel drugs targeting neurological disorders.
  • Peptide Synthesis: It is commonly used in the synthesis of peptides, where its unique fluorinated structure can enhance the stability and bioactivity of the resulting compounds.
  • Material Science: The compound is explored in the creation of advanced materials, including polymers that require specific properties such as increased thermal stability and chemical resistance.
  • Biochemical Research: Researchers utilize it in studies related to protein folding and enzyme activity, providing insights into molecular interactions that are crucial for understanding biological processes.
  • Fluorine Chemistry: Its application in fluorine chemistry allows for the exploration of new chemical reactions and pathways, offering advantages in creating compounds with enhanced pharmacological profiles.

Citations