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Catalog Number:
16572
CAS Number:
84348-38-9
Boc-4-methylene-L-proline
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-4-methylene-L-proline, (S-4-Methylenepyrrolidine-1,2-dicarboxylic acid1-tert butyl ester
Documents
$100.05 /250MG
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Product Information

Boc-4-methylene-L-proline is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its unique structural features, which enhance the stability and bioactivity of peptides. Its Boc (tert-butyloxycarbonyl) protecting group allows for selective reactions, making it an ideal choice for researchers looking to create complex peptide sequences with improved pharmacological properties.

In the pharmaceutical industry, Boc-4-methylene-L-proline is used in the synthesis of various bioactive compounds, including those targeting neurological disorders and cancer therapies. Its ability to facilitate the formation of cyclic peptides and its compatibility with various coupling reagents make it a preferred choice for chemists aiming to optimize their synthetic pathways. Additionally, the compound's favorable solubility profile and stability under physiological conditions further enhance its applicability in drug formulation and development.

Synonyms
Boc-4-methylene-L-proline, (S-4-Methylenepyrrolidine-1,2-dicarboxylic acid1-tert butyl ester
CAS Number
84348-38-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H17NO4
Molecular Weight
227.26
MDL Number
MFCD01861787
PubChem ID
21762564
Melting Point
110-115 °C
Appearance
White to beige solid
Optical Rotation
[α]D22 = -36 ± 2º (C=1 g/100mL in CHCl3)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-4-methylene-L-proline, (S-4-Methylenepyrrolidine-1,2-dicarboxylic acid1-tert butyl ester
CAS Number
84348-38-9
Purity
≥ 99% (HPLC)
Molecular Formula
C11H17NO4
Molecular Weight
227.26
MDL Number
MFCD01861787
PubChem ID
21762564
Melting Point
110-115 °C
Appearance
White to beige solid
Optical Rotation
[α]D22 = -36 ± 2º (C=1 g/100mL in CHCl3)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-methylene-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Drug Development: Its unique structure allows for modifications that can enhance the efficacy and selectivity of drug candidates, making it essential in medicinal chemistry.
  • Bioconjugation: Boc-4-methylene-L-proline is used in bioconjugation processes, facilitating the attachment of biomolecules to therapeutic agents, which can improve targeted delivery in cancer treatments.
  • Research in Neuroscience: This compound is explored in studies related to neurotransmitter modulation, providing insights into potential treatments for neurological disorders.
  • Material Science: Its properties are leveraged in the development of novel materials, including hydrogels and polymers, which have applications in drug delivery systems.

Citations