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Catalog Number:
16627
CAS Number:
147266-92-0
Boc-trans-4-hydroxy-D-proline
Purity:
≥ 95% (NMR)
Synonym(s):
Boc-(2R,4S-4-hydroxypyrrolidine-2-carboxylic acid
Documents
$86.23 /250MG
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Product Information

Boc-trans-4-hydroxy-D-proline is a valuable compound widely utilized in the fields of medicinal chemistry and peptide synthesis. This amino acid derivative features a Boc (tert-butyloxycarbonyl) protecting group, which enhances its stability and solubility, making it an ideal choice for researchers focused on developing bioactive peptides and pharmaceuticals. Its unique trans configuration and hydroxyl group contribute to its ability to facilitate the formation of stable peptide bonds, thereby improving the efficiency of peptide synthesis processes.

In addition to its role in peptide synthesis, Boc-trans-4-hydroxy-D-proline has shown potential in drug design, particularly in the development of inhibitors for various biological targets. Its structural properties allow for the incorporation into cyclic peptides, which are known for their enhanced biological activity and stability. Researchers can leverage this compound to explore novel therapeutic avenues, making it a crucial component in the toolkit of chemists and biochemists aiming to innovate in drug discovery and development.

Synonyms
Boc-(2R,4S-4-hydroxypyrrolidine-2-carboxylic acid
CAS Number
147266-92-0
Purity
≥ 95% (NMR)
Molecular Formula
C10H17F2NO5
Molecular Weight
231.25
MDL Number
MFCD01861341
PubChem ID
335255
Melting Point
122°C
Appearance
White powder
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-(2R,4S-4-hydroxypyrrolidine-2-carboxylic acid
CAS Number
147266-92-0
Purity
≥ 95% (NMR)
Molecular Formula
C10H17F2NO5
Molecular Weight
231.25
MDL Number
MFCD01861341
PubChem ID
335255
Melting Point
122°C
Appearance
White powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-trans-4-hydroxy-D-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating cyclic peptides that are important in drug development.
  • Pharmaceutical Development: It is used in the design of new pharmaceuticals, especially those targeting specific protein interactions, enhancing the efficacy of drug candidates.
  • Biotechnology: In the field of biotechnology, it plays a role in the modification of proteins to improve their stability and functionality, which is crucial for therapeutic applications.
  • Research on Collagen: This compound is significant in studies related to collagen and its derivatives, aiding in the development of materials for tissue engineering and regenerative medicine.
  • Chiral Auxiliary in Organic Synthesis: It acts as a chiral auxiliary, facilitating asymmetric synthesis processes that are essential in creating enantiomerically pure compounds, which are vital in various chemical industries.

Citations