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Catalog Number:
16646
CAS Number:
208259-66-9
Fmoc-(R-2-thienylglycine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-(2-thienyl)glycine
Documents
$100.05 /25MG
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Product Information

Fmoc-(R)-2-thienylglycine is a valuable building block in peptide synthesis, particularly favored for its unique thiophene side chain that enhances the structural diversity of peptides. This compound is widely utilized in the pharmaceutical and biotechnology industries for the development of novel therapeutics, especially in the design of peptide-based drugs. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide sequences while providing stability during synthesis. Researchers appreciate its ability to improve solubility and bioactivity, making it an ideal choice for drug discovery and development.

In addition to its applications in medicinal chemistry, Fmoc-(R)-2-thienylglycine is also employed in the synthesis of functionalized materials and as a precursor in the preparation of various bioactive compounds. Its unique properties enable the creation of peptides with enhanced pharmacological profiles, paving the way for innovative treatments in areas such as cancer therapy and antimicrobial agents. With its versatility and effectiveness, this compound stands out as a crucial tool for researchers aiming to push the boundaries of peptide chemistry.

Synonyms
Fmoc-L-(2-thienyl)glycine
CAS Number
208259-66-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD02094452
PubChem ID
46737303
Melting Point
172-178 °C
Appearance
White powder
Optical Rotation
[a]D25 = +47 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-(2-thienyl)glycine
CAS Number
208259-66-9
Purity
≥ 98% (HPLC)
Molecular Formula
C21H17NO4S
Molecular Weight
379.43
MDL Number
MFCD02094452
PubChem ID
46737303
Melting Point
172-178 °C
Appearance
White powder
Optical Rotation
[a]D25 = +47 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-(R)-2-thienylglycine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: Its unique structure makes it valuable in the development of novel pharmaceuticals, especially in targeting specific biological pathways, enhancing the efficacy of drug candidates.
  • Bioconjugation: Fmoc-(R)-2-thienylglycine can be used to create bioconjugates, linking peptides to other biomolecules, which is essential in creating targeted therapies and diagnostic tools.
  • Research in Neuroscience: This compound is explored for its potential applications in neuroscience, particularly in studying receptor interactions and developing neuroactive compounds.
  • Material Science: It is also being investigated for use in creating functional materials, such as hydrogels, which can be utilized in drug delivery systems and tissue engineering.

Citations