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Catalog Number:
16785
CAS Number:
1217759-04-0
Fmoc-D-2-carbamoylphenylalanine
Purity:
≥ 99% (HPLC, Chiral purity)
Synonym(s):
Fmoc-(2R-2-amino-3-(2-carbamoylphenyl)propanoic acid
Documents
$86.23 /100MG
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Product Information

Fmoc-D-2-carbamoylphenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective modification of amino acids during solid-phase peptide synthesis. Its unique structure, characterized by the incorporation of a carbamoylphenyl group, enhances the compound's stability and solubility, making it an excellent choice for researchers focused on developing complex peptides with improved pharmacological properties.

In practical applications, Fmoc-D-2-carbamoylphenylalanine is particularly valuable in the synthesis of bioactive peptides and pharmaceuticals, where precise control over amino acid sequences is crucial. Its ability to provide a stable and easily removable protecting group allows for streamlined synthesis processes, reducing the time and effort required in laboratory settings. Researchers in medicinal chemistry and biochemistry will find this compound indispensable for advancing their work in peptide-based therapeutics and drug discovery.

Synonyms
Fmoc-(2R-2-amino-3-(2-carbamoylphenyl)propanoic acid
CAS Number
1217759-04-0
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
MDL Number
MFCD06659135
PubChem ID
53398423
Appearance
White to off-white solid
Optical Rotation
[a]D25 = + 62 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-(2R-2-amino-3-(2-carbamoylphenyl)propanoic acid
CAS Number
1217759-04-0
Purity
≥ 99% (HPLC, Chiral purity)
Molecular Formula
C25H22N2O5
Molecular Weight
430.45
MDL Number
MFCD06659135
PubChem ID
53398423
Appearance
White to off-white solid
Optical Rotation
[a]D25 = + 62 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-2-carbamoylphenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide chains with high purity and yield.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, which can target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The compound is used in bioconjugation techniques to attach peptides to other molecules, such as antibodies or drugs, improving the delivery and targeting of therapeutic agents.
  • Research in Cancer Therapy: Its applications extend to cancer research, where it aids in the design of peptide inhibitors that can selectively target cancer cells, potentially leading to more effective treatments.
  • Protein Engineering: Researchers utilize this compound in protein engineering to modify proteins for improved stability and function, which is crucial in developing new biotechnological applications.

Citations