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Catalog Number:
16795
CAS Number:
170642-29-2
Fmoc-D-cyclopropylalanine
Purity:
≥ 99.9% (Chiral HPLC)
Documents
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Product Information

Fmoc-D-cyclopropylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a cyclopropyl side chain, which imparts unique steric and electronic properties, making it an excellent choice for researchers looking to enhance the stability and bioactivity of peptides. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing compatibility with various coupling reagents, facilitating efficient synthesis processes.

In pharmaceutical research, Fmoc-D-cyclopropylalanine has been employed to create peptides with improved pharmacokinetic profiles, potentially leading to more effective therapeutic agents. Its distinctive structure can also be leveraged in the design of novel compounds for targeted drug delivery systems. Researchers in medicinal chemistry and biochemistry will find this compound particularly beneficial for developing innovative solutions in drug design and synthesis, making it a versatile addition to any laboratory's toolkit.

CAS Number
170642-29-2
Purity
≥ 99.9% (Chiral HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD02259484
PubChem ID
4712596
Melting Point
162 - 168 °C
Appearance
White powder
Optical Rotation
[a]D20 = +15 ±2 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
General Information
CAS Number
170642-29-2
Purity
≥ 99.9% (Chiral HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD02259484
PubChem ID
4712596
Melting Point
162 - 168 °C
Appearance
White powder
Optical Rotation
[a]D20 = +15 ±2 °(C=1 in DMF)
Conditions
Store at 0 - 8 °
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-cyclopropylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and diverse peptide libraries.
  • Drug Development: Its unique structure can enhance the bioactivity of peptide-based drugs, making it an important component in the pharmaceutical industry for developing new therapeutics.
  • Protein Engineering: Researchers use this compound to modify proteins, improving their stability and functionality, which is crucial in biotechnological applications.
  • Research on Cyclopropyl Amino Acids: It provides insights into the effects of cyclopropyl groups on biological activity, aiding in the design of novel compounds with specific properties.
  • Bioconjugation: Fmoc-D-cyclopropylalanine can be utilized in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and therapeutic applications.

Citations