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Catalog Number:
16836
CAS Number:
486460-09-7
Boc-D-2,4,5-trifluorophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-(R-2,4,5-trifluorophenylalanine
Documents
$72.31 /100MG
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Product Information

Boc-D-2,4,5-trifluorophenylalanine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and medicinal chemistry. This compound is particularly valued for its unique trifluorophenyl group, which enhances the lipophilicity and metabolic stability of peptides, making it an excellent choice for researchers focused on drug development and protein engineering. Its protective Boc (tert-butyloxycarbonyl) group allows for selective deprotection, facilitating the synthesis of complex peptides with high purity and yield.

In the pharmaceutical industry, Boc-D-2,4,5-trifluorophenylalanine is utilized in the design of peptide-based therapeutics, especially in the development of inhibitors and modulators for various biological targets. Its distinct properties enable researchers to explore innovative approaches in drug discovery, particularly in the fields of oncology and neurology, where peptide-based drugs are gaining traction. With its ability to improve the pharmacokinetic profiles of peptides, this compound stands out as a valuable tool for scientists aiming to create effective and targeted therapies.

Synonyms
Boc-(R-2,4,5-trifluorophenylalanine
CAS Number
486460-09-7
Purity
≥ 99% (HPLC)
Molecular Formula
C14H16F3NO4
Molecular Weight
319.28
MDL Number
MFCD06659118
PubChem ID
21911206
Melting Point
109-115 °C
Appearance
White powder
Optical Rotation
[a]D25 = -3 ± 1º (C=1 in EtOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-(R-2,4,5-trifluorophenylalanine
CAS Number
486460-09-7
Purity
≥ 99% (HPLC)
Molecular Formula
C14H16F3NO4
Molecular Weight
319.28
MDL Number
MFCD06659118
PubChem ID
21911206
Melting Point
109-115 °C
Appearance
White powder
Optical Rotation
[a]D25 = -3 ± 1º (C=1 in EtOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-2,4,5-trifluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique trifluorophenyl group enhances the stability and bioactivity of the resulting peptides.
  • Drug Development: Researchers leverage its properties to design and optimize drug candidates, especially in the fields of oncology and neurology, where specific targeting of receptors is crucial.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing for the attachment of drugs to antibodies or other biomolecules, enhancing the efficacy of targeted therapies.
  • Fluorinated Amino Acids: Its incorporation into proteins can improve their pharmacokinetic properties, making it valuable in the study of protein structure and function, particularly in drug design.
  • Research in Chemical Biology: The compound is instrumental in chemical biology studies, helping scientists understand the interactions between proteins and small molecules, which is vital for the development of new therapeutic strategies.

Citations