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Catalog Number:
16837
CAS Number:
324028-27-5
Boc-L-2,4,5-trifluorophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-(S-2,4,5-trifluorophenylalanine
Documents
$79.22 /100MG
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Product Information

Boc-L-2,4,5-trifluorophenylalanine is a specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique trifluorophenyl group, which enhances its bioactivity and stability, making it an attractive choice for researchers in medicinal chemistry and biochemistry. Its protective Boc (tert-butyloxycarbonyl) group allows for selective reactions during peptide coupling, facilitating the synthesis of complex peptides with improved pharmacological properties.

This compound is particularly valuable in the development of peptide-based therapeutics, where the incorporation of fluorinated amino acids can significantly influence the biological activity and metabolic stability of the resulting peptides. Researchers have utilized Boc-L-2,4,5-trifluorophenylalanine in various applications, including the design of inhibitors for specific enzymes and the development of novel drug candidates targeting various diseases. Its unique properties make it a versatile tool for advancing research in drug discovery and development.

Synonyms
Boc-(S-2,4,5-trifluorophenylalanine
CAS Number
324028-27-5
Purity
≥ 99% (HPLC)
Molecular Formula
C14H16F3NO4
Molecular Weight
319.28
MDL Number
MFCD06659127
PubChem ID
21911206
Melting Point
118-124 °C
Appearance
White powder
Optical Rotation
[a]D25 = +5 ± 1º (C=1 in EtOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-(S-2,4,5-trifluorophenylalanine
CAS Number
324028-27-5
Purity
≥ 99% (HPLC)
Molecular Formula
C14H16F3NO4
Molecular Weight
319.28
MDL Number
MFCD06659127
PubChem ID
21911206
Melting Point
118-124 °C
Appearance
White powder
Optical Rotation
[a]D25 = +5 ± 1º (C=1 in EtOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-2,4,5-trifluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutics targeting specific biological pathways.
  • Drug Development: Its unique fluorinated structure enhances the pharmacokinetic properties of drug candidates, making it valuable in the pharmaceutical industry for creating more effective medications.
  • Bioconjugation: The compound is used in bioconjugation techniques, allowing researchers to attach biomolecules to drugs or imaging agents, improving targeting and efficacy in treatments.
  • Research in Protein Engineering: It plays a significant role in the modification of proteins, aiding in the study of protein structure and function, which is crucial for understanding diseases.
  • Fluorine Chemistry Studies: The presence of fluorine allows for unique interactions in chemical reactions, making it a subject of interest in fluorine chemistry research.

Citations