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Catalog Number:
16839
CAS Number:
959579-81-8
Fmoc-L-2,4,5-trifluorophenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-(S)-2,4,5-trifluorophenylalanine
Documents
$83.32 /100MG
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Product Information

Fmoc-L-2,4,5-trifluorophenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique trifluorophenyl group, which enhances its hydrophobicity and stability, making it an excellent choice for researchers focused on developing novel therapeutic peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains, facilitating the synthesis of complex structures with high purity and yield.

In the pharmaceutical industry, Fmoc-L-2,4,5-trifluorophenylalanine serves as a critical building block for the design of peptide-based drugs, particularly in the development of inhibitors and modulators targeting specific biological pathways. Its distinct properties enable researchers to explore innovative applications in areas such as cancer therapy, antimicrobial agents, and neuropharmacology. By choosing this compound, professionals can enhance their research capabilities and streamline the synthesis of high-quality peptides, ultimately contributing to advancements in therapeutic development.

Synonyms
Fmoc-(S)-2,4,5-trifluorophenylalanine
CAS Number
959579-81-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.4
MDL Number
MFCD06659142
PubChem ID
53398422
Melting Point
152 - 158 °C (Lit.)
Appearance
White powder/solid
Optical Rotation
[a]D20 = -42 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-(S)-2,4,5-trifluorophenylalanine
CAS Number
959579-81-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H18F3NO4
Molecular Weight
441.4
MDL Number
MFCD06659142
PubChem ID
53398422
Melting Point
152 - 158 °C (Lit.)
Appearance
White powder/solid
Optical Rotation
[a]D20 = -42 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-2,4,5-trifluorophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enabling researchers to create complex biomolecules for various applications.
  • Drug Development: Its unique fluorinated structure can enhance the pharmacological properties of peptide-based drugs, making it valuable in pharmaceutical research aimed at developing more effective therapeutics.
  • Bioconjugation: The compound is useful in bioconjugation techniques, allowing for the attachment of peptides to other molecules, such as antibodies or drugs, which can improve targeting and efficacy in treatments.
  • Fluorine-Containing Compounds: Its incorporation into research on fluorinated compounds can lead to the development of novel materials with unique properties, beneficial in fields like materials science and nanotechnology.
  • Analytical Chemistry: Fmoc-L-2,4,5-trifluorophenylalanine can be used as a standard in analytical methods, aiding in the quantification and characterization of peptides in various biological samples.

Citations